Results 71 to 80 of about 11,227 (296)

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Comprehensive Assessment of Air, Soil, and Water Pollution for Environmental Health in Al-Hai City, Iraq

open access: yesمجلة علوم ذي قار
Sustainability has evolved into a broad phrase that includes practically every aspect of life on the Earth, from local to global, and over different periods. Sustainable biological systems include healthy, long-lived forests and wetlands.
Jamal Al Rukabie, Ali Sabeeh Ali
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Tummali ajalugu. Mõningaid märkusi muistsete Sumeri kuningate ja nende kuningavõimu ideoloogia kohta [PDF]

open access: yesMäetagused, 2013
The current short but very important Sumerian literary text, which was written in the Sumerian language at the end of the reign of Ur III (2112–2004 BCE) or at the beginning of the Isin-Larsa epoch (ca 21st or 20th century BCE), consists of only 33 lines.
Vladimir Sazonov
doaj  

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Simulation study of heat transfer behaviour of turbulent two-phase flow in a 3D cubic shell and tube heat exchanger using water and different nanofluids

open access: yesResults in Engineering
This research utilizes a two-phase flow model to replicate the thermal exchange in a counter flow shell and tube heat exchanger, comparing the efficacy of different nanofluids against pure water.
Ali Khaleel Kareem   +2 more
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

Effet du contexte et de l’expérience sur la passation de l’enquête Sumer 2009 par les médecins du travail et influence de la posture professionnelle

open access: yes, 2011
L‘objet de la recherche proposée est de comprendre comment la passation de l’enquête SUMER s’inscrit dans l’activité globale du médecin du travail pour en déduire les effets sur la construction du diagnostic de la situation de travail du salarié dans le ...
Landry, Aurélie   +2 more
core   +3 more sources

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