Results 81 to 90 of about 129,441 (306)

Simulation study of heat transfer behaviour of turbulent two-phase flow in a 3D cubic shell and tube heat exchanger using water and different nanofluids

open access: yesResults in Engineering
This research utilizes a two-phase flow model to replicate the thermal exchange in a counter flow shell and tube heat exchanger, comparing the efficacy of different nanofluids against pure water.
Ali Khaleel Kareem   +2 more
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Self-absorption in the solar transition region

open access: yes, 2015
Transient brightenings in the transition region of the Sun have been studied for decades and are usually related to magnetic reconnection. Recently, absorption features due to chromospheric lines have been identified in transition region emission lines ...
Barczynski, Krzysztof   +9 more
core   +1 more source

Stability of scour protection due to earthquake-induced liquefaction:centrifuge modelling [PDF]

open access: yes, 2017
A key aspect of permanent offshore structures is protection against scour. This is typically in the form of a blanket of coarse gravel or cobbles surrounding the structure.
A.J. Brennan   +28 more
core   +2 more sources

Estimating Reliability for Frechet (3+1) Cascade Model

open access: yesJambura Journal of Mathematics
In this paper, the mathematical formula of the reliability function of a special (3+1) cascade model is found, where this model can work with three active components if it is able to cope with the stresses to which it is subjected, while the cascade 3+1 ...
Ahmed Haroon Khaleel
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Spectroscopy of very hot plasma in non-flaring parts of a solar limb active region: spatial and temporal properties

open access: yes, 2017
In this work we investigate the thermal structure of an off-limb active region in various non-flaring areas, as it provides key information on the way these structures are heated. In particular, we concentrate in the very hot component (>3 MK) as it is a
del Zanna, Giulio   +6 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Tummali ajalugu. Mõningaid märkusi muistsete Sumeri kuningate ja nende kuningavõimu ideoloogia kohta [PDF]

open access: yesMäetagused, 2013
The current short but very important Sumerian literary text, which was written in the Sumerian language at the end of the reign of Ur III (2112–2004 BCE) or at the beginning of the Isin-Larsa epoch (ca 21st or 20th century BCE), consists of only 33 lines.
Vladimir Sazonov
doaj  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

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