Results 31 to 40 of about 2,084,287 (284)

Depression in Osteoporotic and Osteopenic Patients and the Relation with Lifstyle

Türk Osteoporoz Dergisi, 2004
The aims of this study were to investigate the frequency of depression in osteoporotic and osteopenic women and to determine the relationship between depression and lifestyle, level of education and some risk factors of osteoporosis. Sixty-one osteopenic
Evren Kul Panza, Zeynep Güven, Gülseren Akyüz, Demet Ofluoğlu   +3 more
doaj  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

National greenhouse gas inventory document of Japan. 2025 (CGER-report ; CGER-I174-2025) [PDF]

content reviewed by Decarbonized Society Promotion Office, Global Environment Bureau, Ministry of the Environment, Japan primary authors Greenhouse Gas Inventory Office of Japan, Center for Global Environmental Research, Earth System Division, National ...
Greenhouse Gas Inventory Office of Japan (GIO)
core   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Inventory/Asset Management

, 1993
EXECUTIVE SUMMARY -- INTRODUCTION -- FINDINGS -- VEHICLES AND HEAVY EQUIPMENT -- BUILDINGS -- INVENTORY AND CENTRAL WAREHOUSING -- VEHICLES AND HEAVY EQUIPMENT -- BUILDINGS -- BUILDING CONSTRUCTION/RENOVATION -- BUILDING MAINTENANCE -- LEASE PROCESS ...
Reinventing Kansas Government Steering Committee, Inventory/Asset Management Team
core   +1 more source

Munimenta in a turtoise chest. Archival materials in the world of things of Krzysztof Grzymułtowski

Archiwa - Kancelarie - Zbiory, 2017
Krzysztof Grzymułtowski (+1687) was one of most influential Greater Poland landowner of his times. Thanks to his and his mother’s marriages he became related with Leszczyński and Opaliński families.
Marcin Hlebionek, Jagoda Jankowska
doaj   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Comparison of Urban Forest Inventory & Management Software Systems

EDIS, 2009
FOR-226, a 13-page illustrated fact sheet by Michael G. Andreu, Erin M. Brown, Melissa H. Friedman, Robert J. Northrop, and Mary E. Thornhill, examines many of the tree inventory software systems available as of 2009.
Michael G. Andreu, Erin M. Brown, Melissa H. Friedman, Robert J. Northrop, Mary E. Thornhill   +4 more
doaj   +2 more sources