Results 131 to 140 of about 300,823 (367)

Human Cyclophilins—An Emerging Class of Drug Targets

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova   +3 more
wiley   +1 more source

SUMO-2 and PIAS1 Modulate Insoluble Mutant Huntingtin Protein Accumulation

open access: yesCell Reports, 2013
A key feature in Huntington disease (HD) is the accumulation of mutant Huntingtin (HTT) protein, which may be regulated by posttranslational modifications.
Jacqueline Gire O’Rourke   +23 more
doaj   +1 more source

The SUMO Ship Detector Algorithm for Satellite Radar Images

open access: yesRemote Sensing, 2017
Search for Unidentified Maritime Objects (SUMO) is an algorithm for ship detection in satellite Synthetic Aperture Radar (SAR) images. It has been developed over the course of more than 15 years, using a large amount of SAR images from almost all ...
H. Greidanus   +5 more
semanticscholar   +1 more source

SUMOylation regulates LKB1 localization and its oncogenic activity in liver cancer [PDF]

open access: yes, 2019
BACKGROUND: Even though liver kinase B1 (LKB1) is usually described as a tumor suppressor in a wide variety of tissues, it has been shown that LKB1 aberrant expression is associated with bad prognosis in Hepatocellular Carcinoma (HCC).
Díaz Moreno, Irene   +4 more
core   +1 more source

Robustness Assessment of Public Transport Networks in Various Graph Representations: Systematic Review, Decision Support, and Case Study

open access: yesNetworks, EarlyView.
ABSTRACT The analysis of certain properties of the underlying graph of a public transport network generates insights about the network's structure. Hereby, the choice of the graph representation depends on a trade‐off between complexity reduction and information preservation to adequately model a public transport network.
Michael Palk   +2 more
wiley   +1 more source

Risky business [PDF]

open access: yes
Financial institutions ; Credit ; Banks and ...
Vanessa Sumo
core  

Proteome Analysis of Corynebacterium diphtheriae–Macrophage Interaction

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Contact of Corynebacterium diphtheriae with macrophages induces adaptations on both bacterial and cellular sides. The study presented here was aiming to shed light on the simultaneous intracellular adaptation of the bacteria and changes in the proteome of the phagocytes in response to the internalization of C. diphtheriae.
Luca Musella   +6 more
wiley   +1 more source

Trophic factor BDNF inhibits GABAergic signaling by facilitating dendritic enrichment of SUMO E3 ligase PIAS3 and altering gephyrin scaffold [PDF]

open access: gold, 2022
Zahra S. Thirouin   +6 more
openalex   +1 more source

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