Results 131 to 140 of about 291,935 (374)
Fiscal sweeteners : Did North Carolina lure Dell too much? [PDF]
State finance ; Revenue ; Federal Reserve District ...
Vanessa Sumo
core
The SUMO Pathway in Hematomalignancies and Their Response to Therapies
International Journal of Molecular Sciences, 2019 SUMO (Small Ubiquitin-related MOdifier) is a post-translational modifier of the ubiquitin family controlling the function and fate of thousands of proteins.
Mathias Boulanger +3 more
semanticscholar +1 more source
Interdisciplinary Medicine, EarlyView.Background: Mitochondrial fission protein (FIS1), affecting energy metabolism and homeostasis, is crucial for mitochondrial quality control (MQC) and tumor progression. Key Points: It varies in expression across TME, influencing tumor progression.
Chao Wei +7 more
wiley +1 more source
Mechanism of Adenovirus E4-ORF3-Mediated SUMO Modifications
mBio, 2019 Regulation of a variety of different cellular processes, including posttranslational modifications, is critical for the ability of many viruses to replicate efficiently within host cells.
Sook-Young Sohn, Patrick Hearing
doaj +1 more source
A role for SUMO modification in transcriptional repression and activation [PDF]
, 2007 Since the discovery of the SUMO (small ubiquitin-like modifier) family of proteins just over a decade ago, a plethora of substrates have been uncovered including many regulators of transcription.
David +26 more
core +1 more source
The ubiquitin-like modifier FAT10 interferes with SUMO activation
Nature Communications, 2019 The covalent attachment of the cytokine-inducible ubiquitin-like modifier HLA-F adjacent transcript 10 (FAT10) to hundreds of substrate proteins leads to their rapid degradation by the 26 S proteasome independently of ubiquitylation.
Annette Aichem +8 more
semanticscholar +1 more source
Commentary: Three questions for the study of traumatic brain injury in animals
The Anatomical Record, EarlyView.
Gregory Hollin
wiley +1 more source
Human Cyclophilins—An Emerging Class of Drug Targets
Medicinal Research Reviews, EarlyView.ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova +3 more
wiley +1 more source
SUMO-2 and PIAS1 Modulate Insoluble Mutant Huntingtin Protein Accumulation
Cell Reports, 2013 A key feature in Huntington disease (HD) is the accumulation of mutant Huntingtin (HTT) protein, which may be regulated by posttranslational modifications.
Jacqueline Gire O’Rourke +23 more
doaj +1 more source