Results 151 to 160 of about 46,190 (264)
The role of the nucleus in the control of mitochondrial precursor proteins in yeast
Abstract Mitochondria are essential organelles of eukaryotic cells, with vital roles in energy production, biosynthesis of macromolecules, and intracellular signaling. Their function depends on a complex proteome with proteins targeted to different mitochondrial sub‐compartments.
Kira Ritzenhofen +3 more
wiley +1 more source
Abstract Alzheimer's disease (AD) is characterized by the intracellular aggregation of the microtubule‐associated protein Tau. While the presence of large, insoluble neurofibrillary tangles has long been the primary focus of this research, a paradigm shift in the field now highlights smaller, soluble oligomers as the more neurotoxic Tau species leading
Joshua T. Skrehot, Dmitry Kurouski
wiley +1 more source
Catcher domains function as highly versatile fusion tags that simultaneously enhance soluble protein expression and enable modular protein assembly. Spontaneous, irreversible covalent coupling by Catcher‐Tag pairs provides a platform for downstream modular engineering, enabling oriented enzyme immobilization, protein polymerization, and selective ...
Ruxia Fan +6 more
wiley +1 more source
Abstract Polyploidization has played a key role in plant genome evolution. Eragrostis curvula (Schrad.) Ness, a perennial forage grass species of the Poaceae family, is an excellent model for investigating genome duplication due to its natural variation in ploidy levels.
D. F. Santoro +5 more
wiley +1 more source
The graphical abstract compares methanol and presolubilized PCL as external carbon sources in anoxic batch denitrification tests. Although both substrates showed comparable biomass yields, presolubilized PCL supported a higher maximum growth rate than methanol.
Dorsa Barkhordari +6 more
wiley +1 more source
Modeling Bus Traffic for the Berlin SUMO Traffic Scenario
The digital transformation of the transport sector in our cities will be led by the deployment of large-scale digital twins, interacting with their real world counterpart to model, predict, and improve movements and reoccurring patterns.
Schweppenhäuser, Moritz +4 more
core +1 more source
Human Absorption, Metabolism, and Excretion (hAME) Mass Balance Studies in Patients With Cancer
ABSTRACT Radiolabeled mass balance human studies are a critical component of clinical pharmacology programs supporting the development of new investigational drugs. These studies provide information about absorption, metabolism, and excretion (AME) of the parent drug and metabolite(s) in the human body and are normally conducted in healthy volunteers ...
Begoña de las Heras +9 more
wiley +1 more source
Traffic signal control logic programs are analyzed and tested in traffic fow simulators before being put into operation in real traffic road intersections.
Erdmann, Jakob +4 more
core

