Results 151 to 160 of about 46,190 (264)

The role of the nucleus in the control of mitochondrial precursor proteins in yeast

open access: yesProtein Science, Volume 35, Issue 6, June 2026.
Abstract Mitochondria are essential organelles of eukaryotic cells, with vital roles in energy production, biosynthesis of macromolecules, and intracellular signaling. Their function depends on a complex proteome with proteins targeted to different mitochondrial sub‐compartments.
Kira Ritzenhofen   +3 more
wiley   +1 more source

Biophysical assessment of the molecular mechanisms of Tau aggregation and its role in Alzheimer's disease

open access: yesProtein Science, Volume 35, Issue 6, June 2026.
Abstract Alzheimer's disease (AD) is characterized by the intracellular aggregation of the microtubule‐associated protein Tau. While the presence of large, insoluble neurofibrillary tangles has long been the primary focus of this research, a paradigm shift in the field now highlights smaller, soluble oligomers as the more neurotoxic Tau species leading
Joshua T. Skrehot, Dmitry Kurouski
wiley   +1 more source

Catcher Domains as Multifunctional Fusion Modules for Soluble Expression, Covalent Coupling, and Spatial Organization of Recombinant Proteins

open access: yesSmall Science, Volume 6, Issue 6, June 2026.
Catcher domains function as highly versatile fusion tags that simultaneously enhance soluble protein expression and enable modular protein assembly. Spontaneous, irreversible covalent coupling by Catcher‐Tag pairs provides a platform for downstream modular engineering, enabling oriented enzyme immobilization, protein polymerization, and selective ...
Ruxia Fan   +6 more
wiley   +1 more source

SUMO [PDF]

open access: yesMolecular Cell, 2005
openaire   +1 more source

Traversing the effects of ploidy changes in different Eragrostis curvula genotypes through high‐throughput RNA sequencing

open access: yesThe Plant Genome, Volume 19, Issue 2, June 2026.
Abstract Polyploidization has played a key role in plant genome evolution. Eragrostis curvula (Schrad.) Ness, a perennial forage grass species of the Poaceae family, is an excellent model for investigating genome duplication due to its natural variation in ploidy levels.
D. F. Santoro   +5 more
wiley   +1 more source

A multilevel approach to individual and organizational predictors of stress and fatigue among healthcare workers of Paris university hospitals: A longitudinal analysis from the STRIPPS survey

open access: yesSafety and Health at Work, 2022
Oumou Salama Daouda   +6 more
doaj   +1 more source

Decoupling Dissolution and Biological Kinetics in Polycaprolactone‐Based Denitrification: Direct Determination of Yield and Maximum Specific Growth Rate

open access: yesWater Environment Research, Volume 98, Issue 6, June 2026.
The graphical abstract compares methanol and presolubilized PCL as external carbon sources in anoxic batch denitrification tests. Although both substrates showed comparable biomass yields, presolubilized PCL supported a higher maximum growth rate than methanol.
Dorsa Barkhordari   +6 more
wiley   +1 more source

Modeling Bus Traffic for the Berlin SUMO Traffic Scenario

open access: yes
The digital transformation of the transport sector in our cities will be led by the deployment of large-scale digital twins, interacting with their real world counterpart to model, predict, and improve movements and reoccurring patterns.
Schweppenhäuser, Moritz   +4 more
core   +1 more source

Human Absorption, Metabolism, and Excretion (hAME) Mass Balance Studies in Patients With Cancer

open access: yesClinical and Translational Science, Volume 19, Issue 6, June 2026.
ABSTRACT Radiolabeled mass balance human studies are a critical component of clinical pharmacology programs supporting the development of new investigational drugs. These studies provide information about absorption, metabolism, and excretion (AME) of the parent drug and metabolite(s) in the human body and are normally conducted in healthy volunteers ...
Begoña de las Heras   +9 more
wiley   +1 more source

LiSuM: Design and Development of a Middleware to couple Virtual LISA+ TLS Controller and SUMO Simulation

open access: yes, 2017
Traffic signal control logic programs are analyzed and tested in traffic fow simulators before being put into operation in real traffic road intersections.
Erdmann, Jakob   +4 more
core  

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