Results 211 to 220 of about 1,958,325 (325)

SUMO-Activating Enzyme Subunit 1 (SAE1) is A Promising Diagnostic Cancer Metabolism Biomarker of Hepatocellular Carcinoma [PDF]

open access: green, 2020
Jiann Ruey Ong   +6 more
openalex   +1 more source

Histone deacetylase genes in lotus seed maturation: Identification and expression pattern analysis

open access: yeseFood, Volume 6, Issue 5, October 2025.
Fourteen HDACs were identified and characterized from lotus seed. NnHDA3 may be involved in the maturation and senescence of lotus seeds. NnHDA2 and NnSRT1 are involved in the metabolism of chlorophyll and starch during lotus seed ripening. Abstract Histone deacetylase (HDAC) plays an essential role in plant growth, development, and maturation ...
Shiqi Zheng   +7 more
wiley   +1 more source

Guanine Nucleotide Exchange Factors and Small GTPases: Their Regulation and Functions, Diseases, and Therapeutic Targets

open access: yesMedComm, Volume 6, Issue 10, October 2025.
This review comprehensively examines the regulatory mechanisms and physiological roles of guanine nucleotide exchange factors (GEFs) and their small GTPase substrates, highlighting their significance in cellular processes and disease pathogenesis.
Zexing Lin   +15 more
wiley   +1 more source

Loss of the E2 SUMO-conjugating enzyme Ube2i in oocytes during ovarian folliculogenesis causes infertility in mice

open access: bronze, 2019
Amanda Rodriguez   +9 more
openalex   +1 more source

Mitochondria‐Associated Endoplasmic Reticulum Membranes in Health and Diseases

open access: yesMedComm, Volume 6, Issue 10, October 2025.
As pivotal regulators in diverse physiological and pathological processes, mitochondria‐associated endoplasmic reticulum membranes (MAMs) are critically involved in both health and diseases, including cancers, neurodegenerative disorders, metabolic diseases, cardiovascular diseases.
Hangnan Hong   +3 more
wiley   +1 more source

Free Radicals in Health and Disease

open access: yesMedComm, Volume 6, Issue 10, October 2025.
Free radicals have dual roles that can either selectively create oxidative damages to transformed cells in treating proliferative diseases such as cancers and some dermatological disorders or boost the antioxidant system in treating degenerative diseases such as neurodegenerative disorder, joint degeneration, and metabolic conditions.
Xiaofeng Dai, Zizheng Huang, Ruohan Lyu
wiley   +1 more source

UFMylation System: Biological Functions, Molecular Mechanisms, Diseases, and Drug Discovery

open access: yesMedComm, Volume 6, Issue 10, October 2025.
UFMylation, a novel ubiquitin‐like modification, plays an essential role in various cellular processes, such as the immune response, DNA damage repair, unfolded protein response (UPR), autophagy, endoplasmic reticulum (ER)‐phagy, stem cell self‐renewal, apoptosis, and metastasis.
Huiyan Li   +5 more
wiley   +1 more source

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