Results 81 to 90 of about 288 (212)

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Monotonicity character of convex combinations of two sequences generated by the square of the cube root function

Journal of Inequalities and Applications
There is a natural connection between the finite sums of the reciprocals of the squares of the cube roots of positive natural numbers and two definite integrals.
Stevo Stević, Bratislav Iričanin, Witold Kosmala, Zdeněk Šmarda   +3 more
doaj   +1 more source

A Learner-Refiner Framework for Barrier Certificate Generation

Mathematics
Barrier certificate is a powerful tool for verifying they safety property of dynamical systems. In this paper, we introduce an innovative learner–refiner framework for synthesizing polynomial barrier certificates.
Deng Chen, Wang Lin, Zuohua Ding
doaj   +1 more source

Sums of Squares on Hypersurfaces

Results in Mathematics
We show that the Pythagoras number of rings of type $\mathbb{R}[x,y, \sqrt{f(x,y)}]$ is infinite, provided that the polynomial $f(x,y)$ satisfies some mild conditions.
Kacper Błachut, Tomasz Kowalczyk
openaire   +3 more sources

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

On The Eigenvalue Distribution Of Adjacency Matrices For Connected Planar Graphs

Quaestiones Geographicae, 2015
This paper describes the previously unknown statistical distribution of adjacency matrix spectra for planar graphs, also known as spatial weights matrices, in terms of the following three readily available eigenvalue properties: extremes, rank orderings,
Griffith Daniel A.
doaj   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Hypoellipticity and Non Hypoellipticity for Sums of Squares of Complex Vector Fields

Bruno Pini Mathematical Analysis Seminar, 2011
In this talk we give a report on a paper where we consider a model sum of squares of planar complex vector fields, being close to Kohn's operator but with a point singularity.
Antonio Bove
doaj