Results 41 to 50 of about 24,999 (231)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

EXPONENTIAL SUMS OVER POINTS OF ELLIPTIC CURVES WITH RECIPROCALS OF PRIMES [PDF]

open access: yes, 2017
We consider exponential sums with x-coordinates of points qG and q−1G where G is a point of order T on an elliptic curve modulo a prime p and q runs through all primes up toN (with gcd (q,T)=1 in the case of the points q−1G).
Ostafe, Alina, Shparlinski, Igor E.
core  

On Weyl sums over primes and almost primes

open access: yesMichigan Mathematical Journal, 2006
In the paper under review, new estimates are established for exponential sums over primes of the form \[ f(\alpha)=\sum\limits_{P\leq p0\) is an absolute constant, and the implied \(\ll\)-constant depends at most on \(k\) and \(\varepsilon\). The above bound for \(f(\alpha)\) is then employed to make progress on several questions related to the Waring ...
openaire   +3 more sources

ON WEYL SUMS OVER PRIMES IN SHORT INTERVALS [PDF]

open access: yesNumber Theory: Arithmetic in Shangri-La, 2013
The main results extend to sums over primes in a short interval earlier estimates by the author for "long" Weyl sums over primes.
openaire   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Congruences for Wolstenholme primes [PDF]

open access: yes, 2011
A prime number $p$ is said to be a Wolstenholme prime if it satisfies the congruence ${2p-1\choose p-1} \equiv 1 \,\,(\bmod{\,\,p^4})$. For such a prime $p$, we establish the expression for ${2p-1\choose p-1}\,\,(\bmod{\,\,p^8})$ given in terms of the ...
Mestrovic, Romeo
core  

A High‐Sensitivity Circulating Nucleic Acid Sequencing Assay for Assessing Treatment Response to Alectinib in a Pediatric Patient With ALK‐Rearranged Non–Small Cell Lung Cancer

open access: yes
Pediatric Blood &Cancer, EarlyView.
Alberto D. Guerra   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy