Results 111 to 120 of about 9,115 (211)

Calciprotein particle‐induced calcium overload triggers mitochondrial dysfunction in endothelial cells

The Journal of Physiology, EarlyView.
Abstract figure legend Calciprotein particles (CPPs) are small calcium‐ and phosphate‐containing nanoaggregates associated with the development of vascular disease (CVD) in chronic kidney disease (CKD). Previously, we have shown that CPPs induce endothelial cell (EC) dysfunction, possibly contributing to CVD in CKD, but the underlying molecular ...
Lian Feenstra, Laurent Chatre, Benoit Bernay, Julien Pontin, Mirjam F. Mastik, Azuwerus van Buiten, Dalibor Nakládal, Bastiaan S. Star, Jan‐Luuk Hillebrands, Guido Krenning   +9 more
wiley   +1 more source

High-throughput plasma/serum proteomics by coupling nanoparticle protein corona-based sample preparation and capillary zone electrophoresis-tandem mass spectrometry.

Anal Methods
Wang Q, Sadeghi SA, Fang F, Zheng D, Luo C, Gao G, Wang Q, Gu B, Sun L.   +8 more
europepmc   +1 more source

Multi-Scale simulation of electromagnetic wave excitation by positive corona discharge in SF₆ gas. [PDF]

Sci Rep
Bin F, Yao C, Feng J, Liang F, Sun Q.
europepmc   +1 more source

Metabolite‐sensitive cross‐bridge models of human atria reveal the impact of diabetes on muscle mechanoenergetics

The Journal of Physiology, EarlyView.
Abstract figure legend In this study, we used mathematical modelling to explore the effect of diabetes on muscle mechanoenergetics. Our parameterisation of cross‐bridge models using data from non‐diabetic and diabetic human atrial tissues revealed lower values for cross‐bridge stiffness, detachment rates, attachment rates and lower ATP sensitivity in ...
Julia H. Musgrave, June‐Chiew Han, Marie‐Louise Ward, Andrew J. Taberner, Kenneth Tran   +4 more
wiley   +1 more source

A bimodal longitudinal investigation on changes in sentiments over social media interactions owing to COVID-19 pandemic. [PDF]

Sci Rep
Anik MSH, Rabi N, Eliza IJ, Hisham MHH, Akil A, Turza AM, Feroz F, Morshed F, Sakib N, Noor J, Chellappan S, Islam ABMAA.   +11 more
europepmc   +1 more source

Insights from animal models: Dissecting the independent roles of oxygen and nutrients in the fetal origins of cardiovascular disease

The Journal of Physiology, EarlyView.
Abstract figure legend This review utilized animal models of complicated human pregnancies that result in reduced fetal nutrient or oxygen delivery, or combined nutrient and oxygen delivery, to elucidate their independent and/or synergistic contributions to the development of high‐risk cardiac phenotypes.
Melanie R. Bertossa, Jack R. T. Darby, Ashley S. Meakin, Mitchell C. Lock, Steven K. S. Cho, Christopher K. Macgowan, Mike. Seed, Michael D. Wiese, Janna L. Morrison   +8 more
wiley   +1 more source

A novel dual-targeting strategy of nanobody-driven protein corona modulation for glioma therapy. [PDF]

Acta Pharm Sin B
Zhang Y, Qin S, Song T, Huang Z, Lv Z, Zhao Y, Jiao X, Sun M, Zhang Y, Xie G, Chen Y, Ruan X, Liu R, Shi H, Yang C, Zhao S, He Z, Huang H, Song X.   +18 more
europepmc   +1 more source

Circular RNAs: Unlocking new avenues in cardiometabolic disease management

The Journal of Physiology, EarlyView.
Abstract figure legend In the heart circular RNAs (circRNAs) function as microRNA sponges, interact with proteins and can even undergo translation. Advances in bioinformatics now enable their identification through high‐throughput RNA sequencing, whereas computational analyses reveal differential expression in cardiac disease settings.
Kimberley M. Mellor, Thomas D. Donelly, Gerald L.M. Naepi, Glenn D. Wadley, Bianca C. Bernardo   +4 more
wiley   +1 more source

Type 2 diabetes mellitus associated microRNAs in tuberculosis susceptibility: a systematic review and bioinformatic analysis. [PDF]

Front Endocrinol (Lausanne)
Chávez-Domínguez RL, Viettri M, Torres M, Corona-Galvan IA, Hernández-Diego E, Castañón-Arreola M, Carranza C.   +6 more
europepmc   +1 more source

The impact of pay‐for‐performance incentives for stroke unit access on public hospital costs and use, Queensland, 2012–17: interrupted time series analysis

Medical Journal of Australia, Volume 222, Issue 5, Page 249-258, March 2025.
Abstract Objectives To assess the impact of pay‐for‐performance financial incentives for improving stroke unit access in Queensland public hospitals on hospital costs and use. Study design Population‐based longitudinal study; interrupted time series analysis of linked hospital admissions, emergency department, and hospital costs data.
Rohan Grimley, Joosup Kim, Helen M Dewey, Nadine E Andrew, Taya A Collyer, Eleanor S Horton, Greg Cadigan, Dominique A Cadilhac   +7 more
wiley   +1 more source