Results 121 to 130 of about 9,230 (211)

Calciprotein particle‐induced calcium overload triggers mitochondrial dysfunction in endothelial cells

The Journal of Physiology, EarlyView.
Abstract figure legend Calciprotein particles (CPPs) are small calcium‐ and phosphate‐containing nanoaggregates associated with the development of vascular disease (CVD) in chronic kidney disease (CKD). Previously, we have shown that CPPs induce endothelial cell (EC) dysfunction, possibly contributing to CVD in CKD, but the underlying molecular ...
Lian Feenstra, Laurent Chatre, Benoit Bernay, Julien Pontin, Mirjam F. Mastik, Azuwerus van Buiten, Dalibor Nakládal, Bastiaan S. Star, Jan‐Luuk Hillebrands, Guido Krenning   +9 more
wiley   +1 more source

The impact of periodic leg movements during sleep on neurological recovery in patients with acute mild cerebral infarction. [PDF]

Front Neurol
Sun S, Zheng Y, Xu L, Yu W, Jing T, Xu G, Tang T, Chu C.   +7 more
europepmc   +1 more source

Metabolite‐sensitive cross‐bridge models of human atria reveal the impact of diabetes on muscle mechanoenergetics

The Journal of Physiology, EarlyView.
Abstract figure legend In this study, we used mathematical modelling to explore the effect of diabetes on muscle mechanoenergetics. Our parameterisation of cross‐bridge models using data from non‐diabetic and diabetic human atrial tissues revealed lower values for cross‐bridge stiffness, detachment rates, attachment rates and lower ATP sensitivity in ...
Julia H. Musgrave, June‐Chiew Han, Marie‐Louise Ward, Andrew J. Taberner, Kenneth Tran   +4 more
wiley   +1 more source

Multi-Scale simulation of electromagnetic wave excitation by positive corona discharge in SF₆ gas. [PDF]

Sci Rep
Bin F, Yao C, Feng J, Liang F, Sun Q.
europepmc   +1 more source

Human placental exposure to pollutant nanoparticles: uptake, translocation and functional impact

The Journal of Physiology, EarlyView.
Abstract figure legend Prenatal exposure to pollutant nanoparticles has been increasingly investigated due to concerns about their potential effects on placental function and pregnancy outcomes. Maternal inhalation of pollutant nanoparticles can result in a pro‐inflammatory response; particles can also translocate across the alveolus epithelial barrier
Katherine L. Bethell, Andrew C. Povey, Edward D. Johnstone, Peter T. Ruane   +3 more
wiley   +1 more source

Web-based LAS-FNAME and blood biomarkers in autosomal dominant Alzheimer's disease. [PDF]

Alzheimers Dement (Amst)
Gonzalez Corona C, Ospina Lopera P, Rowe MC, Vila-Castelar C, Giudicessi A, Malotaux V, He B, Tristão-Pereira C, Martinez JE, Osorio Asprilla L, Ramírez Gallego MS, Alzate Echeverri DP, Serna L, Ashton NJ, Cuello AC, Aguillon D, Quiroz YT.   +16 more
europepmc   +1 more source

Insights from animal models: Dissecting the independent roles of oxygen and nutrients in the fetal origins of cardiovascular disease

The Journal of Physiology, EarlyView.
Abstract figure legend This review utilized animal models of complicated human pregnancies that result in reduced fetal nutrient or oxygen delivery, or combined nutrient and oxygen delivery, to elucidate their independent and/or synergistic contributions to the development of high‐risk cardiac phenotypes.
Melanie R. Bertossa, Jack R. T. Darby, Ashley S. Meakin, Mitchell C. Lock, Steven K. S. Cho, Christopher K. Macgowan, Mike. Seed, Michael D. Wiese, Janna L. Morrison   +8 more
wiley   +1 more source

A novel dual-targeting strategy of nanobody-driven protein corona modulation for glioma therapy. [PDF]

Acta Pharm Sin B
Zhang Y, Qin S, Song T, Huang Z, Lv Z, Zhao Y, Jiao X, Sun M, Zhang Y, Xie G, Chen Y, Ruan X, Liu R, Shi H, Yang C, Zhao S, He Z, Huang H, Song X.   +18 more
europepmc   +1 more source

Circular RNAs: Unlocking new avenues in cardiometabolic disease management

The Journal of Physiology, EarlyView.
Abstract figure legend In the heart circular RNAs (circRNAs) function as microRNA sponges, interact with proteins and can even undergo translation. Advances in bioinformatics now enable their identification through high‐throughput RNA sequencing, whereas computational analyses reveal differential expression in cardiac disease settings.
Kimberley M. Mellor, Thomas D. Donelly, Gerald L.M. Naepi, Glenn D. Wadley, Bianca C. Bernardo   +4 more
wiley   +1 more source