Results 51 to 60 of about 9,230 (211)

Lipid Profile in Primary Aldosteronism: Cross‐Sectional and Post‐Treatment Analyses

open access: yesLipids, EarlyView.
ABSTRACT The relationship between primary aldosteronism (PA) and lipid metabolism remains controversial, with inconsistent findings reported in the literature. This study aimed to clarify PA's impact on the lipid profile using both a cross‐sectional comparison with essential hypertension (EH) controls and a longitudinal within‐patient pre‐post ...
Meriem Yazidi   +7 more
wiley   +1 more source

Recent Advances (2023–2025) of Capillary Electrophoresis‐Mass Spectrometry (CE‐MS) for Top‐Down Proteomics

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT Top‐down proteomics (TDP) characterizes proteoforms in cells, tissues, and biofluids, in discovery mode and on a global scale, requiring analytical tools with high peak capacity for proteoform separation and high sensitivity for proteoform detection, given the extremely high proteoform complexity and wide proteoform concentration dynamic range.
Guijie Zhu   +5 more
wiley   +1 more source

Circadian Immunity and Vascular Inflammation in Cardiovascular Disease Chronotherapy Windows: Time for a Re‐Assessment

open access: yesMed Research, EarlyView.
ABSTRACT Circadian rhythms orchestrate cardiovascular physiology by regulating immune and inflammatory pathways. Disruption of these rhythms profoundly alters vascular homeostasis, thereby promoting the onset and progression of cardiovascular diseases (CVD).
Tian Zhang   +22 more
wiley   +1 more source

White Adipose Tissue Browning and Cross Talk With Metabolic Diseases and Tumors: From Molecular Mechanisms to Clinical Translation

open access: yesMed Research, EarlyView.
White adipose tissue undergoes browning under endogenous and exogenous stimuli, primarily regulated by core molecules such as PRDM16 and UCP1. It exhibits a double‐edged sword effect in metabolic diseases and tumors: while mitigating metabolic disease impacts and suppressing early‐stage tumors through nutritional competition, it may accelerate cachexia
Yingjiao Wang   +12 more
wiley   +1 more source

The Application of Telemedicine in Surgery

open access: yesMed Research, EarlyView.
This figure provides an overview of the content presented in this article. Telemedicine is integrated throughout the entire surgical workflow, with distinct applications across the preoperative, intraoperative, and postoperative phases. These applications are enabled by a suite of supporting technologies, while the associated implementation challenges ...
Yufan Yang   +8 more
wiley   +1 more source

Inflammation, Immunity, and Cardiovascular Diseases

open access: yesMed Research, EarlyView.
Cardiovascular stress signals (e.g., hemodynamic shear, oxidized lipids, and ischemia) act on endothelial and immune cells to activate and amplify inflammation through NF‐κB, the NLRP3 inflammasome, and JAK/STAT signaling, inducing proinflammatory cytokines/chemokines (IL‐6, IL‐1β, TNF‐α, and CCL2) and self‐amplifying circuits; clinically, inflammatory
Dezhi Guo   +8 more
wiley   +1 more source

Radiometric Constraints on the Timing, Tempo, and Effects of Large Igneous Province Emplacement

open access: yesGeophysical Monograph Series, Page 27-82., 2021

Exploring the links between Large Igneous Provinces and dramatic environmental impact

An emerging consensus suggests that Large Igneous Provinces (LIPs) and Silicic LIPs (SLIPs) are a significant driver of dramatic global environmental and biological changes, including mass extinctions.
Jennifer Kasbohm   +2 more
wiley  

+3 more sources

Development and Validation of a Nomogram Incorporating Preoperative N‐Terminal Pro‐Brain Natriuretic Peptide to Predict Major Adverse Cardiovascular Events in Renal Transplant Recipients

open access: yesOrgan Medicine, EarlyView.
We developed and validated a preoperative nomogram incorporating NT‐proBNP to predict major adverse cardiovascular events in renal transplant recipients. Using a LASSO‐Cox model based on 582 training and 181 validation cases, we identified NT‐proBNP, age, body mass index, diabetes, and retransplantation as key predictors.
Guobin Wu   +9 more
wiley   +1 more source

Electrospun conducting polymers: recent trends and the transition towards a sustainable future

open access: yesPolymer International, EarlyView.
This review discusses the electrospinning of conducting polymers, detailing procedures, fibrous morphologies, improved properties, applications in electronics, and challenges, while outlining future directions for nanofibre‐based devices in various fields.
Xenofon Karagiorgis   +3 more
wiley   +1 more source

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