Results 61 to 70 of about 9,445 (213)
Mass Spectrometry Reviews, EarlyView.ABSTRACT Top‐down proteomics (TDP) characterizes proteoforms in cells, tissues, and biofluids, in discovery mode and on a global scale, requiring analytical tools with high peak capacity for proteoform separation and high sensitivity for proteoform detection, given the extremely high proteoform complexity and wide proteoform concentration dynamic range.
Guijie Zhu +5 more
wiley +1 more source
Mass Spectrometry Insights Into Post‐Translational Modifications in Extracellular Vesicles
Mass Spectrometry Reviews, EarlyView.ABSTRACT Extracellular vesicles (EVs) are membrane‐enclosed structures secreted by virtually all living cells, serving as essential mediators of intercellular communication in both physiological and pathological processes. There is growing interest in their potential applications as biomarkers, therapeutic targets, and drug delivery systems, which ...
Dávid Virág +5 more
wiley +1 more source
The Application of Telemedicine in Surgery
Med Research, EarlyView.This figure provides an overview of the content presented in this article. Telemedicine is integrated throughout the entire surgical workflow, with distinct applications across the preoperative, intraoperative, and postoperative phases. These applications are enabled by a suite of supporting technologies, while the associated implementation challenges ...
Yufan Yang +8 more
wiley +1 more source
Proteomic Signatures of Ectopic Fat Distribution: Tissue‐Specific Drivers and Clinical Implications
Med Research, EarlyView.Integration of plasma proteomics and multi‐organ MRI in 666 UK Biobank participants, combined with a knockoff‐based causal inference and machine learning framework, reveals organ‐specific drivers of ectopic fat: PLA2G1B (pancreas), ERBB2/IGFBP2 (liver), CA14 (muscle), and NCAM2/TNFRSF10B (pericardium). These drivers engage distinct pathways (e.g., PI3K‐
Bing Zhang +9 more
wiley +1 more source
Electrospun conducting polymers: recent trends and the transition towards a sustainable future
Polymer International, EarlyView.This review discusses the electrospinning of conducting polymers, detailing procedures, fibrous morphologies, improved properties, applications in electronics, and challenges, while outlining future directions for nanofibre‐based devices in various fields.
Xenofon Karagiorgis +3 more
wiley +1 more source
Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy
Phytotherapy Research, EarlyView.Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee +9 more
wiley +1 more source
Journal of Field Robotics, EarlyView.ABSTRACT As a crucial puzzle piece of deep space exploration, exploring small bodies can provide significant scientific insights and valuable mineral resources. Unlike missions to the Moon and Mars, small‐body missions pose distinct technical challenges, including communication delays, weak gravity, and uncertain environments. This paper reviews a full
Xin Zhang +3 more
wiley +1 more source
Radiometric Constraints on the Timing, Tempo, and Effects of Large Igneous Province Emplacement
Geophysical Monograph Series, Page 27-82., 2021 Exploring the links between Large Igneous Provinces and dramatic environmental impact
An emerging consensus suggests that Large Igneous Provinces (LIPs) and Silicic LIPs (SLIPs) are a significant driver of dramatic global environmental and biological changes, including mass extinctions.
Jennifer Kasbohm +2 more
wiley +3 more sources
Sustainable Development, EarlyView.ABSTRACT During the last three decades, higher education institutions (HEIs) have integrated sustainability into their curricula. Recent research has focused on sustainability competences and pedagogical approaches, and how the latter foster the development of the former. Previous studies have examined the connections between pedagogical approaches and
Gabriela Ortiz‐Martínez +27 more
wiley +1 more source
Small‐Scale Magnetic Soft Robots for Medical Applications: From Laboratory to Clinical Use
SmartBot, EarlyView.Small‐scale magnetic soft robots are emerging as promising platforms for minimally invasive diagnosis and therapy in complex in vivo environments. This review compares untethered and tethered medical magnetic robots in parallel across five translational stages, from basic performance testing to clinical evaluation.
Xingxing Ke +29 more
wiley +1 more source