Results 111 to 120 of about 29,020 (214)

Lactylation‐Driven PROS1‐TYRO3‐CARF Signaling Promotes Therapy‐Induced Senescence Escape and Radioresistance in Meningioma

open access: yesAdvanced Science, EarlyView.
A glycolysis‐driven epigenetic switch promotes therapy resistance in meningioma. Increased lactate production enhances histone H3K27 lactylation, which activates PROS1 secretion. Secreted PROS1 engages TYRO3 signaling to degrade the senescence regulator CARF, allowing cancer cells to escape growth arrest.
Zhuohang Wang   +12 more
wiley   +1 more source

A Hepatocyte‐to‐Stellate Cell Axis Couples Alternate‐Day Fasting to Liver Fibrosis Resolution via ATG7 S‐Nitrosylation

open access: yesAdvanced Science, EarlyView.
Alternate‐day fasting suppresses mitochondrial complex II assembly via SDHAF4 to upregulate hepatocyte eNOS. The resulting nitric oxide S‐nitrosylates ATG7 at C184 in hepatic stellate cells, restraining autophagic flux and preventing their profibrotic activation.
Xueqiang Wang   +17 more
wiley   +1 more source

A magnetic nanorobot with guided aggregation and thrombin-triggered coagulation for endovascular embolization. [PDF]

open access: yesMater Today Bio
Fan J   +14 more
europepmc   +1 more source

Wood Carbon Sponge/SiO2 Aerogel Composites with Anisotropic Broadband Microwave Absorption, Elastic Resilience, and Thermal Insulation

open access: yesAdvanced Science, EarlyView.
Anisotropic wood carbon sponge/SiO2 aerogel composites are constructed, revealing a robust direction‐dependent permittivity ordering (tangential > radial > axial). The radial direction delivers an ultra‐broadband effective absorption bandwidth of 11.6 GHz at only 4.95 mm, while the tangential direction offers superior compressibility and thermal ...
Shuo Sun   +7 more
wiley   +1 more source

Bio‐Memristor Based on Clinical Bile Samples: A Proof‐of‐Concept Pilot Study for Detection of Gallbladder Cancer

open access: yesAdvanced Science, EarlyView.
In this work, we present a bile‐based memristor hardware framework that enables direct, label‐free identification of cholelithiasis and gallbladder cancer at the device level. The Ag/bile/FTO memristor features stable resistive switching and disease‐specific electrical responses, providing a conceptual foundation for circuits and an integrated ERCP ...
Junming Zhu   +17 more
wiley   +1 more source

Bioenergetic Materials for Tissue Regeneration: Modulating Metabolism to Promote Cellular Anabolism

open access: yesAdvanced Science, EarlyView.
Bioenergetic materials (BEMs) modulate cellular metabolism to promote tissue regeneration. Their principal mechanisms of action include metabolic substrate supplementation, metabolic enzyme modulation, organelle transfer, electrical current regulation, redox homeostasis modulation, and oxygen tension modulation.
Yuchen He   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy