Results 61 to 70 of about 7,837,864 (382)

Prevalence of Earth-size planets orbiting Sun-like stars [PDF]

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2013
Significance A major question is whether planets suitable for biochemistry are common or rare in the universe. Small rocky planets with liquid water enjoy key ingredients for biology.
E. Petigura, A. Howard, G. Marcy
semanticscholar   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

CALIBRATION OF SIBERIAN RADIOHELIOGRAPH IMAGES

open access: yesSolar-Terrestrial Physics, 2019
We discuss the method for automatic calibration of solar radio images derived from the first stage of the multiwave Siberian Radioheliograph (SRH-48). SRH is a 48-element T-shaped radiointerferometer in the 4–8 GHz frequency range. Since the end of 2017,
Fedotova A.Yu.   +4 more
doaj   +1 more source

Multiwave Siberian Radioheliograph

open access: yesSolar-Terrestrial Physics, 2020
The article discusses characteristics, fundamental and applied tasks of the Siberian Radioheliograph that is developed at the ISTP SB RAS Radio Astrophysical Observatory and spectropolarimetric complex that measures the total flux of solar radio emission.
Altyntsev A.T.   +13 more
doaj   +1 more source

Mediterranean Diet and Health Outcomes in the SUN Cohort

open access: yesNutrients, 2018
The Mediterranean Dietary (MedDiet) Pattern has been linked to many beneficial health effects. This review summarizes the main findings of a prospective cohort study, the Seguimiento Universidad de Navarra (SUN) cohort, specifically focused on MedDiet ...
S. Carlos   +6 more
semanticscholar   +1 more source

A Prediction Formula of Supersoft X-ray Phase of Classical Novae

open access: yes, 2009
On the basis of the recently developed universal decline law of classical novae, we propose prediction formulae for supersoft X-ray on and off times, i.e., t_{X-on} = (10 \pm 1.8) t_3 days and t_{X-off} = (5.3 \pm 1.4) (t_3)^{1.5} days for 8 < t_3 < 80 ...
Augusto   +96 more
core   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

Is the F10.7cm – Sunspot Number relation linear and stable?

open access: yesJournal of Space Weather and Space Climate, 2021
The F10.7cm radio flux and the Sunspot Number are the most widely used long-term indices of solar activity. They are strongly correlated, which led to the publication of many proxy relations allowing to convert one index onto the other.
Clette Frédéric
doaj   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

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