Results 231 to 240 of about 1,325,224 (290)

Respiratory and bloodstream coinfections and antimicrobial use in hospitalised patients with moderate to severe COVID-19: An Australian retrospective cohort study. [PDF]

PLoS One
Frederiksen L, Subedi S, Choong K, Anderson J, Baird T.   +4 more
europepmc   +1 more source

Macrophage RSAD2 Couples mtDNA Synthesis With a Self‐Amplifying Inflammatory Circuit to Orchestrate Tissue Repair

Advanced Science, EarlyView.
Macrophage RSAD2 dually regulates CMPK2—the rate‐limiting enzyme for mitochondrial DNA synthesis—by suppressing its ubiquitination and promoting its phosphorylation via Csnk2a2 recruitment. This amplifies mtDNA production, which simultaneously activates a cGAS‐STING‐IRF3‐RSAD2 feedforward loop and the NLRP3 inflammasome, driving a self‐sustaining ...
Haomiao Yuan, Shukui Du, Chunfei Li, Xinjie Li, Shuyang Mu, Anran Qu, Hengxu Yan, Chongchong Xu, Jinnong Yang, Jingkai Sun, Yijun Wang, Jiayang Xiao, Fuyuan Zhang, Linlin Wang, Tiegang Li, Rui Zhao, Dawei Guan   +16 more
wiley   +1 more source

A high-resolution historical long-term gridded daily meteorological data set for agricultural climate change analysis in Japan. [PDF]

Data Brief
Ishigooka Y, Kuwagata T, Yoshimoto M, Hasegawa T, Nishimori M, Takimoto T, Wakatsuki H, Toda Y.   +7 more
europepmc   +1 more source

Climatic Τrends and periodicities in Sunshine Duration

, 1980
Bloutsos, Antonios, Angouridakis, V. E.
openaire   +1 more source

DIXDC1 Promotes Lymphatic Metastasis and Resistance to Cuproptosis in Bladder Cancer Through Mediating DLAT

Advanced Science, EarlyView.
DIXDC1 drives bladder cancer progression by binding and stabilizing DLAT. This axis enhances NEK7 and CCNE2 mRNA stability to promote proliferation and lymphatic metastasis, while limiting copper‐induced DLAT oligomerization to reduce cuproptosis sensitivity, identifying DIXDC1 as a potential target linking metastasis with cuproptosis resistance ...
Hongqiong Li, Liang Cheng, Xiaole Lu, Haonan Dong, Shi Fu, Hongjin Shi, Mingsheng Liu, Chenwei Yang, Yuhang Huang, Zehua Chen, Yawei Zhang, Kaiwen Jie, Xiaoyue Zhang, Xiang Kui, Xinni Ye, Siting Chen, Xu Chen, Haifeng Wang   +17 more
wiley   +1 more source

SSGJ-613 Alleviates Pain and Reduces the Risk of Acute Flares in Patients With Gout: A Randomized, Double-Blind, Phase II Study. [PDF]

Int J Rheum Dis
Xue Y, Zhu X, Zhang B, Li Y, Gou W, Dai L, Zhang N, Tang L, Zhang Z, Dong L, Yang X, Xu J, Li Z, Yang J, Lou J, Liu Y, Zou H.   +16 more
europepmc   +1 more source

Arrayed Magnetic Accelerator Synergistically Enhances Orthodontic Tooth Movement via Microtubule Assembly‐Mediated Periodontal Remodeling

Advanced Science, EarlyView.
Mechanical orthodontic treatment for malocclusion is limited by slow remodeling and risks due to poor biomechanical sensing. This study shows that static magnetic fields (SMFs) enhance mechanical sensation in periodontal ligament cells, promoting inflammation and osteoclast activity.
Yiling Lou, Jiwei Sun, Peng Chen, Caihong Mao, Junyuan Zhang, Haoqi Lei, Xiaoqing Han, Yaxuan Zhang, Yuheng Jiang, Yulin Jia, Bin Su, Lili Chen   +11 more
wiley   +1 more source

Daily relationship between air pollution and physical activity in an industrial region. [PDF]

Appl Psychol Health Well Being
Knapová L, Lískovec R, Cho YW, Baretta D, Keller J, Elavsky S.   +5 more
europepmc   +1 more source

Presentations of idiopathic hemorrhagic diarrhea syndrome in dogs in relation to meteorological factors. [PDF]

J Vet Intern Med
Karnstedt M, Asif A, Sibanda TZ, Heilmann RM.   +3 more
europepmc   +1 more source