Results 181 to 190 of about 1,248,900 (279)

Dissecting the angiogenic mechanism of pachychoroid polypoidal choroidal vasculopathy

iMeta, Volume 5, Issue 5, October 2026.
A prognosis‐oriented classification system was established to distinguish Pachy PCV from Non‐pachy PCV using a large multicenter dataset. Comparative plasma multi‐omics profiling of Pachy PCV, Non‐pachy PCV, and normal controls revealed unique upregulation of the fluid shear stress and atherosclerosis (FSS‐AS) and HIF‐1 signaling pathways in Pachy PCV.
Xinyu Zhao, Tiantian Cheng, Wenfei Zhang, Xingwang Gu, Qing Zhao, Yaning Chen, Lihui Meng, Jiaqi Zhang, Bintao Qiu, Lili Li, Shiyu Cheng, Zicheng Wang, Chuting Wang, Yuelin Wang, Zuyi Yang, Zhengming Shi, Ye Guo, Shengzhi Liu, Youxin Chen   +18 more
wiley   +1 more source

The influence of solar-modulated regional circulations and galactic cosmic rays on global cloud distribution. [PDF]

Sci Rep, 2023
Kumar V, Dhaka SK, Hitchman MH, Yoden S.
europepmc   +1 more source

Molecular and Cellular Underpinnings of Primary Hypertension: An Integrative Mechanistic Framework

Journal of Cellular Physiology, Volume 241, Issue 10, October 2026.
ABSTRACT Hypertension is a highly prevalent clinical condition and a major contributor to global cardiovascular morbidity and mortality. Despite extensive research, its complex and multifaceted pathogenesis is yet to be fully elucidated. This paper explores the updated understanding of primary hypertension as a systemic disorder rather than an isolated
Dima Nasrallah, Alaa Abdelhamid, Omar Tluli, Yaman Al‐Haneedi, Mera Abu Hussien, Ali H. Eid   +5 more
wiley   +1 more source

Extremely active Sun from 1190 to 1220 in the Medieval Period: Intercomparison of historical records and tree-ring carbon-14. [PDF]

Proc Jpn Acad Ser B Phys Biol Sci
Miyahara H, Kataoka R, Yamamoto K, Tokanai F, Moriya T, Takeyama M, Sakurai H, Ohyama M, Horiuchi K, Hotta H.   +9 more
europepmc   +1 more source

Spatiotemporal Changes and Climate Driving Factors of Compound Precipitation‐Temperature Extreme Events Across Global Land Areas

International Journal of Climatology, Volume 46, Issue 12, October 2026.
During the period 1901–2024, the dominant proportion of compound dry‐warm extremes in annual, June–July–August (JJA), and December–January–February (DJF) occurrences was the highest among the four types of compound precipitation and temperature extremes across global land areas, accounting for 40.1%, 50.3%, and 28.0%, respectively.
Ruting Yang, Silong Zhang, Xiongpeng Tang, Chao Gao, Haibin Zhang, Xin Yin, Yanli Liu   +6 more
wiley   +1 more source

Polar Faculae and the Polar Magnetic Field in Solar Cycles 24 and 25. [PDF]

Sol Phys
Clark JR, Pesnell WD, Barzal MC.
europepmc   +1 more source

Mesenchymal Stem Cell‐Derived Extracellular Vesicles Ameliorate NaIO3‐Induced Dry AMD by Delivering miR‐486‐3p to Inhibit Lipocalin‐2‐Mediated Ferroptosis

MedComm, Volume 7, Issue 10, October 2026.
Our study reveals a novel mechanism by which MSC‐derived EVs alleviate NaIO3‐induced dry AMD‐like pathology. MSC‐EVs deliver miR‐486‐3p into retinal cells to directly inhibit the ferroptosis‐promoting target gene Lcn2. Concurrently, downregulated Lcn2 restores intracellular Gpx4 expression, thereby suppressing ferroptosis and rescuing retinal ...
Zheng Li, Tujing Zhao, Lin Ye, Runze Li, Huaping Tian, Ruilin Liao, Lulin Huang   +6 more
wiley   +1 more source

Decadal East Asian monsoon anomalies and implications for societal conflicts. [PDF]

Sci Adv
Zhao K, Liang Y, Huang C, Wang Y, Sun W, Cheng H, Yin J, Hu D, Yan M, Ning L, Yu Z, Edwards RL.   +11 more
europepmc   +1 more source

Macular microvascular assessment in glaucoma: Tool output comparison and intersession reliability

Optometry and Vision Science, Volume 103, Issue 10, October 2026.
ABSTRACT Purpose To compare outputs and evaluate the intersession reliability of macular vascular metrics from the Erlangen‐Angio (EA)‐tool and the optical coherence tomography angiography vascular analyser (OCTAVA) Tool in glaucoma. Methods Ninety‐three participants with open‐angle glaucoma from the Individualised Perimetry Progression Observations in
Kowsigan Magesan, Vanessa T. S. Tang, Siavash Salmanzadeh, William H. Morgan, Geoffrey Chan, Allison M. McKendrick   +5 more
wiley   +1 more source

Multivariate Frequency and Amplitude Estimation for Unevenly Sampled Data Using and Extending the Lomb-Scargle Method. [PDF]

Sensors (Basel)
Seilmayer M, Wondrak T, Garcia F.
europepmc   +1 more source