Results 161 to 170 of about 11,976 (273)

Single‐Cell RNA Sequencing of Retina Reveals Nna1 Upregulation in Myopic Diabetic Retinopathy as a Protective Factor Against Diabetic Damage

open access: yesAdvanced Science, Volume 13, Issue 5, 27 January 2026.
This study investigates a schematic overview of the mechanistic pathways. The relationship between myopia and DR has long been of clinical interest. In diabetic mice, Nna1 expression is downregulated, whereas in diabetic mice with FDM, Nna1 expression is upregulated–particularly in Müller cells–accompanied by decreased vascular endothelial growth ...
Lihui Xie   +5 more
wiley   +1 more source

Continuous Suppression of Pathological Retinal and Choroidal Neovascularization in Cynomolgus Monkeys via Noninvasive Ophthalmic Delivery of a Novel Anti‐VEGFA Nanobody and Proprietary Penetratin Analog Formulation

open access: yesAdvanced Science, Volume 13, Issue 1, 5 January 2026.
Pathological retinal/choroidal neovascularization drives vision loss in DR and AMD. Current anti‐VEGF injections, while effective, require invasive, frequent administration. Pene/LQ015, is developed a novel topical anti‐VEGFA nanobody formulation achieving therapeutic intraocular levels through penetratin analog‐enhanced delivery.
Chong Chen   +12 more
wiley   +1 more source

Atypical Retinitis Pigmentosa With Macular Sparing in a Patient With Compound Heterozygous ABCA4 Variants: A Case Report and Diagnostic Challenge

open access: yesClinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT Inherited retinal dystrophies are a complex group of disorders causing progressive vision loss. The ABCA4 gene is associated with a wide spectrum of retinopathies, most commonly Stargardt disease, which is characterized by central macular degeneration.
Na Li, Yalong Dang
wiley   +1 more source

Infrared camouflage in leaf-sitting frogs: a cautionary tale on adaptive convergence. [PDF]

open access: yesJ R Soc Interface
Stuart-Fox D   +4 more
europepmc   +1 more source

Beyond Treatment: The Strategy of Nonintervention in Choroidal Hemangioma

open access: yesClinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT The circumscribed choroidal hemangioma (CCH) is a benign congenital eye tumor whose etiology is not clear. A 41‐year‐old female patient came with a 2‐year history of slowly progressive deteriorating vision in her right eye. In the left eye, the best‐corrected visual acuity (BCVA) was 6/6, and counting fingers at 1 m in the right eye.
Humdan Khan   +8 more
wiley   +1 more source

Butterfly Diagram and Other Properties of Plage Areas from Kodaikanal Ca ii K Photographs Covering 1904 - 2007. [PDF]

open access: yesSol Phys
Jha BK   +6 more
europepmc   +1 more source

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