Results 41 to 50 of about 32,288 (217)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
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An Optimal Initial Partitioning of Large Data Model in Utility Management Systems
Advances in Electrical and Computer Engineering, 2011 Modern Utility Management Systems which utilize multiprocessor systems for efficient processing of large data model are considered in this paper. The necessary preconditions for the efficient calculation are optimal load balancing of processors and ...
SVENDA, G. +3 more
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Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
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Shenzhen Daxue xuebao. Ligong banThe filling height during the construction phase has a significant impact on the mechanical properties of super-large-diameter steel bellows arch culverts.
JIANG Tonghui +3 more
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Transmission Network Planning in Super Smart Grids: A Survey
IEEE Access, 2023 For a utility company to reduce $CO_{2}$ emissions along with managing load demands, it must strive for a 100 percent renewable electrical power generation.
Muhammad Adnan +3 more
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
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Field Tests of Super-Long and Large-Diameter Drilled Shaft Pile Foundations
Advances in Civil Engineering, 2020 This study investigated the compressive behaviour of super-long pile foundations with large diameters. Three 52 m, 73 m, and 83 m long piles with a diameter of 1500 mm, 1500 mm, and 1800 mm were cast and tested, respectively. Given that large loading was
Peisen Wang +5 more
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FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
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Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
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Yantu gongcheng xuebaoRock-socketed piles with large diameter have gradually become the preferred foundation type for large-scale structures under complex geological conditions due to their advantages such as high bearing capacity and low settlement.
XIAO Li 1, 2, DU Fenglei 3, 4, ZHAO Mingrui 1, 2, GAO Wensheng 3, WANG Tao 3, JIANG Hongliang 3
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