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Treatment options in pediatric super-refractory status epilepticus
Brain and Development, 2019Super-refractory status epilepticus (SRSE) is a seizure that continues >24 h after anesthesia, or recurs on the reduction of anesthesia. SRSE is extremely difficult-to-control and associated with poor outcome. To date, optimal therapy and outcome data in children is limited.To assess etiology, treatment options and outcome in pediatric SRSE patients.We
Palita, Arayakarnkul +1 more
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Neuromodulation in Super-refractory Status Epilepticus
Journal of Clinical Neurophysiology, 2021Summary: Status epilepticus (SE) is a severe condition that needs immediate pharmacological treatment to tackle brain damage and related side effects. In approximately 20% of cases, the standard treatment for SE does not control seizures, and the condition evolves to refractory SE.
Ioannis, Stavropoulos +2 more
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Super-Refractory Status Epilepticus
Current Neurology and Neuroscience Reports, 2015Although the vast majority of patients with status epilepticus (SE) respond fairly well to the first- or second-line anti-epileptics, a minority require anesthetic agents to put the seizures under control. An even smaller number of patients do not even respond to those and constitute the subgroup of super-refractory SE.
Mauricio Ruiz, Cuero +1 more
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Continuum, 2022
Status epilepticus is a serious condition caused by disorders and diseases that affect the central nervous system. In status epilepticus, hypersynchronous epileptic activity lasts longer than the usual duration of isolated self-limited seizures (time t1), which causes neuronal damage or alteration of neuronal networks at a certain time point (time t2),
Eugen, Trinka, Markus, Leitinger
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Status epilepticus is a serious condition caused by disorders and diseases that affect the central nervous system. In status epilepticus, hypersynchronous epileptic activity lasts longer than the usual duration of isolated self-limited seizures (time t1), which causes neuronal damage or alteration of neuronal networks at a certain time point (time t2),
Eugen, Trinka, Markus, Leitinger
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Status Epilepticus, Refractory Status Epilepticus, and Super-refractory Status Epilepticus
Continuum, 2018Status epilepticus, refractory status epilepticus, and super-refractory status epilepticus can be life-threatening conditions. This article presents an overview of the three conditions and discusses their management and outcomes.Status epilepticus was previously defined as lasting for 30 minutes or longer but now is more often defined as lasting 5 ...
Sarah E, Nelson, Panayiotis N, Varelas
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Status epilepticus: Refractory and super-refractory
Neurology India, 2017Status epilepticus (SE) is an important neurological emergency. It is defined as seizures lasting for 5 minutes or more or recurrent seizures without recovery of consciousness to baseline between the attacks. Refractory SE (RSE) is defined as SE persisting despite sufficient dose of benzodiazepines and at least one antiepileptic drug (AED ...
Deepanshu, Dubey +2 more
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Treatment of Super-Refractory Status Epilepticus
Current Neurology and Neuroscience Reports, 2015Super-refractory status epilepticus (SRSE) is a devastating neurological condition with limited treatment options. We conducted an extensive literature search to identify and summarize the therapeutic options for SRSE. The search mainly resulted in case reports of various pharmacologic and non-pharmacologic treatments.
Ahmad, Bayrlee +3 more
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Predictors of outcome in super refractory status epilepticus
Epilepsy & Behavior, 2021We conducted this study to determine the clinical, electrophysiological and radiological predictors of outcome in Super Refractory Status Epilepticus (SRSE).Data of patients treated for SRSE between January 2000 and November 2019, archived prospectively in our SE registry were analyzed.
Jithu Jose +6 more
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Super-refractory status epilepticus in West China
Acta Neurologica Scandinavica, 2014This study aims to determine the general frequency, mortality, and risk factors of super-refractory status epilepticus (SRSE) versus non-refractory status epilepticus (NRSE) and refractory status epilepticus (RSE).This work is a retrospective study. Clinical data of patients who were diagnosed with status epilepticus (SE) in the neurological ward and ...
L, Tian +6 more
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Electroconvulsive Therapy for Super Refractory Status Epilepticus
The Journal of ECT, 2018Objectives Super refractory status epilepticus (SRSE) is a stage beyond refractory status that requires general anesthesia as management. Electroconvulsive therapy (ECT) is recommended only as a potential treatment option beyond general anesthesia and after all other options have been exhausted.
Jayme, Ahmed +8 more
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