Super-refractory status epilepticus

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Mega‐dose phenobarbital therapy for super‐refractory status epilepticus

Epileptic Disorders, 2015
AbstractAims. To evaluate the efficacy and safety of mega‐dose phenobarbital (MDPB; enteral or parenteral phenobarbital >10 mg/kg/day) for treating super‐refractory status epilepticus (SRSE; continuous or recurrent status epilepticus for ≥24 hours after the onset of continuous anaesthetic treatment) in adult patients.Methods.
Jung-Ick, Byun +14 more
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Stiripentol for the treatment of super-refractory status epilepticus

Acta Neurologica Scandinavica, 2015
To determine whether stiripentol (STP) might be a treatment option in super-refractory status epilepticus (SRSE).Medical records of patients treated due to a status epilepticus in Marburg between January 2013 and June 2014 were reviewed for administration of STP. Primary outcome measures were resolution of SE after initiation of STP.Five adult patients
A, Strzelczyk, L-M, Kortland, S, Knake, F, Rosenow +3 more
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New-onset super-refractory status epilepticus (NOSRSE)

Neurology, 2020
Imagine that your 23-year-old healthy child unexpectedly has a seizure and that seizure will not stop. You rush her to the hospital where seizures continue despite increasing doses of medications. She is intubated, transferred to the neurocritical care unit (NICU), deeply sedated, and put on continuous long-term video-EEG monitoring. Laboratory studies,
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Efficacy of levetiracetam, fosphenytoin, and valproate for established status epilepticus by age group (ESETT): a double-blind, responsive-adaptive, randomised controlled trial

Lancet, The, 2020
Jaideep Kapur, Shlomo Shinnar, Jordan Elm +2 more
exaly

An interesting case of super-refractory status epilepticus