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Chronic HIV-1 Infection Frequently Fails to Protect against Superinfection [PDF]

open access: yesPLoS Pathogens, 2007
Reports of HIV-1 superinfection (re-infection) have demonstrated that the immune response generated against one strain of HIV-1 does not always protect against other strains.
Julie Overbaugh   +2 more
exaly   +3 more sources

Superinfection exclusion: A viral strategy with short-term benefits and long-term drawbacks [PDF]

open access: yesPLoS Computational Biology, 2022
Viral superinfection occurs when multiple viral particles subsequently infect the same host. In nature, several viral species are found to have evolved diverse mechanisms to prevent superinfection (superinfection exclusion) but how this strategic choice ...
Michael Hunter, Diana Fusco
exaly   +14 more sources

Contrasting antibody responses to intrasubtype superinfection with CRF02_AG

open access: yesPLoS ONE, 2017
HIV superinfection describes the sequential infection of an individual with two or more unrelated HIV strains. Intersubtype superinfection has been shown to cause a broader and more potent heterologous neutralizing antibody response when compared to ...
Steve Porcella   +2 more
exaly   +3 more sources

Influenza A Virus Superinfection Potential Is Regulated by Viral Genomic Heterogeneity

open access: yesMBio, 2018
Defining the specific factors that govern the evolution and transmission of influenza A virus (IAV) populations is of critical importance for designing more-effective prediction and control strategies. Superinfection, the sequential infection of a single
Christopher Brooke, Jiayi Sun
exaly   +4 more sources

A Filamentous Bacteriophage Protein Inhibits Type IV Pili To Prevent Superinfection of Pseudomonas aeruginosa

open access: yesMBio, 2022
Pseudomonas aeruginosa is an opportunistic pathogen that causes infections in a variety of settings. Many P. aeruginosa isolates are infected by filamentous Pf bacteriophage integrated into the bacterial chromosome as a prophage.
Patrick Secor   +2 more
exaly   +3 more sources

HIV-1 Superinfection Occurs Less Frequently Than Initial Infection in a Cohort of High-Risk Kenyan Women

open access: yesPLoS Pathogens, 2013
HIV superinfection (reinfection) has been reported in several settings, but no study has been designed and powered to rigorously compare its incidence to that of initial infection.
Keshet Ronen   +2 more
exaly   +3 more sources

Repressive effect of primary virus replication on superinfection correlated with gut-derived central memory CD4(+) T cells in SHIV-infected Chinese rhesus macaques. [PDF]

open access: yesPLoS ONE, 2013
A possible mechanism of susceptibility to superinfection with simian-human immunodeficiency virus (SHIV)-1157ipd3N4 was explored in twelve SHIVSF162P3-infected Chinese rhesus macaques.
Jing Xue   +13 more
doaj   +1 more source

Hepatitis E virus superinfection impairs long-term outcome in hospitalized patients with hepatitis B virus-related decompensated liver cirrhosis

open access: yesAnnals of Hepatology, 2023
Introduction and Objectives: Hepatitis E virus (HEV) superinfection is a common excerbating event in patients with chronic hepatitis B, but the impact on the long-term prognosis is not clear.
Hong Zhao   +7 more
doaj   +1 more source

The Role of Bacterial and Fungal Superinfection in Critical COVID-19

open access: yesViruses, 2022
Background: The range of reported rates of bacterial and fungal superinfections in patients with a severe course of COVID-19 is wide, suggesting a lack of standardised reporting.
Tamara Seitz   +8 more
doaj   +1 more source

HIV Superinfection [PDF]

open access: yesThe Journal of Infectious Diseases, 2005
Worldwide, 16 cases of HIV-1 superinfection in humans have been reported since 2002. Superinfection is defined as the reinfection of an individual who already has an established infection with a heterologous HIV strain. Controversy exists surrounding superinfection, because it has implications concerning our understanding of worldwide HIV diversity ...
Davey M, Smith   +2 more
openaire   +2 more sources

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