Results 111 to 120 of about 45,804 (257)

Hepatitis B in Organ Transplantation—Current Evidence and Clinical Gaps

Transplant Infectious Disease, EarlyView.
ABSTRACT Over the past several decades there have been significant advances in nucleos(t)ide analogue (NA) antiviral therapy for hepatitis B virus (HBV) and global expansion of primary prevention through immunization. Despite this, HBV remains a leading cause of chronic liver disease globally, affecting over 250 million people.
Oscar A. Fernandez‐Garcia, Britta L. Hirsch, Irene A. Abela, Karen E. Doucette   +3 more
wiley   +1 more source

Reactive Astrocyte‐Associated IL‐33 Signaling Contributes to a Protective Neuroimmune State During Chronic Toxoplasma gondii–Plasmodium berghei Coinfection

Glia, Volume 75, Issue 1, January 2027.
Chronic Toxoplasma gondii infection establishes a regulated neuroimmune environment that protects against experimental cerebral malaria without reducing cerebral parasite burden. Coinfection is associated with the emergence of reactive astrocytes displaying an intermediate inflammatory phenotype characterized by the co‐expression of CXCL‐10 and TGF‐β ...
Inès Leleu, Tarun Keswani, Fabien Herbert, Capucine Picavet, Manon Arnaud, Sabrina Marion, Corine Glineur, Sylviane Pied   +7 more
wiley   +1 more source

Exclusion of Superinfection or Enhancement of Superinfection in Pestiviruses—APPV Infection Is Not Dependent on ADAM17

Viruses
Some viruses can suppress superinfections of their host cells by related or different virus species. The phenomenon of superinfection exclusion can be caused by inhibiting virus attachment, receptor binding and entry, by replication interference, or competition for host cell resources. Blocking attachment and entry not only prevents unproductive double
Geranio, Francesco, Affeldt, Sebastian, Cechini, Angelika, Barth, Sandra, Reuscher, Carina M., Riedel, Christiane, Rümenapf, Till, Lamp, Benjamin   +7 more
openaire   +5 more sources

Clinical Features and Predictors of Hospital Stay in Paediatric Epstein–Barr Virus Infectious Mononucleosis: A Multicentre Cohort Study

Acta Paediatrica, Volume 115, Issue 12, Page 2880-2887, December 2026.
ABSTRACT Aim To describe age‐specific clinical features and identify predictors of length of hospital stay in children and adolescents with primary Epstein–Barr virus (EBV) infectious mononucleosis (IM). Methods This multicentre retrospective cohort study included all children and adolescents aged 0–17 years with a verified primary EBV infection in the
Lasse H. Nyhegn, Sara Yde Steffensen, Sabine Frølich Maarbjerg, Luise Borch, Marianne Kragh Thomsen, Mette Holm   +5 more
wiley   +1 more source

HIV-1 superinfection in an HIV-2-infected woman with subsequent control of HIV-1 plasma viremia [PDF]

, 2009
A human immunodeficiency virus type 2 (HIV-2)-infected woman experienced asymptomatic superinfection with HIV-1 subtype AG. She did not have cross-neutralizing autologous HIV-1 antibodies before and shortly after HIV-1 superinfection.
Günthard, H F, Kuster, H, Böni, J, Shah, C, Schüpbach, J, Huber, M, Trkola, A, Kuster H, Böni J, Schüpbach J, Günthard HF, Huber M, Shah C, Trkola A   +13 more
core   +1 more source

Chronic Hepatitis B in the United States: Current Landscape, Unmet Needs and Future Directions

Journal of Viral Hepatitis, Volume 33, Issue 12, December 2026.
ABSTRACT Chronic hepatitis B (CHB) infection represents a major public health challenge in the US, with substantial unmet needs related to timely diagnosis, treatment, monitoring and disease management. This narrative review explores the CHB landscape in the US, including gaps in patient care, the evolving therapeutic landscape, the clinical utility of
Chari Cohen, James Philip Esteban, Shravani Bobde, Robert J. Wong   +3 more
wiley   +1 more source

Interferon Lambda Inhibits Bacterial Uptake during Influenza Superinfection

Infection and Immunity, 2019
Influenza kills 30,000 to 40,000 people each year in the United States and causes 10 times as many hospitalizations. A common complication of influenza is bacterial superinfection, which exacerbates morbidity and mortality from the viral illness ...
Helen E. Rich, C. McCourt, Wen-Quan Zheng, Kevin J. McHugh, K. Robinson, Jie-Ru Wang, J. F. Alcorn   +6 more
semanticscholar   +1 more source

Experimental dissection of phenotypic variation for quantitative disease resistance in canola (Brassica napus) – Leptosphaeria maculans interactions

Pest Management Science, Volume 82, Issue 11, Page 10806-10817, November 2026.
This graphical abstract illustrates how quantitative resistance to Leptosphaeria maculans in canola is experimentally estimated through multi‐environment replicated trials measuring crown canker severity. Genotype, environment and pathogen sources feed into phenotyping, followed by variance partitioning using mixed models and beta regression to ...
Luke G Barrett, Mohamed CM Zakeel, Angela P Van der Wouw, Rebecca Maher, Kurt D Lindbeck, Susan J Sprague   +5 more
wiley   +1 more source

Increased susceptibility to bacterial superinfection as a consequence of innate antiviral responses

, 2006
The reason why severe localized or systemic virus infections enhance and aggravate bacterial superinfection is poorly understood. Here we show that virus-induced IFN type I caused apoptosis in bone marrow granulocytes, drastically reduced granulocyte ...
Recher, Mike, Meury, Susanne, Panco Georgiev, Lukas Flatz, Rolf M. Zinkernagel, Lang, Karl S., Hengartner, Hans, Hans Hengartner, Karl S. Lang, Zinkernagel, Rolf M., Andreas Bergthaler, Odermatt, Bernhard, Bille, Jacques, Alexander A. Navarini, Bergthaler, Andreas, Mike Recher, Landmann, Regine, Bernhard Odermatt, Georgiev, Panco, Jacques Bille, Flatz, Lukas, Susanne Meury, Regine Landmann, Navarini, Alexander A., Navarini AA, Georgiev, P., Hengartner H, Meury S, Recher, M., Landmann, R., Zinkernagel, R. M., Odermatt B, Meury, S., Recher M, Bergthaler, A., Flatz L, Bille J, Georgiev P, Bille, J., Lang KS, Landmann R, Hengartner, H., Lang, K. S., Zinkernagel RM, Navarini, A. A., Odermatt, B., Flatz, L., Bergthaler A   +47 more
core   +1 more source

The Matrix Protein of a Plant Rhabdovirus Mediates Superinfection Exclusion by Inhibiting Viral Transcription

Journal of Virology, 2019
Superinfection exclusion (SIE) is a widespread phenomenon in which an established virus infection prevents reinfection by closely related viruses. Understanding the mechanisms governing SIE will not only advance our basic knowledge of virus infection ...
Xin Zhou, Kai Sun, Xue-Ping Zhou, A. O. Jackson, Zheng-He Li   +4 more
semanticscholar   +1 more source