Results 71 to 80 of about 7,770 (230)

MRI with fibre tracking in Cogan congenital oculomotor apraxia [PDF]

open access: yes, 2018
Background: Congenital ocular motor apraxia (COMA) occasionally shares with Joubert syndrome (JS) and related disorders (JSRDs) a peculiar malformation, the ‘molar tooth sign' (MTS).
De Haller, Raoul   +4 more
core  

Glaucoma animal models in rabbits: State of the art and perspectives—A review

open access: yesAnimal Models and Experimental Medicine, Volume 8, Issue 3, Page 429-440, March 2025.
Glaucoma, a visual thief, is characterized by elevated intraocular pressure (IOP) and loss of retinal ganglion cells (RGCs). Selecting suitable animals for preclinical models is of great significance in research on the prevention, early screening, and effective treatments of glaucoma.
Rong Hu   +4 more
wiley   +1 more source

Histological and Biochemical Alterations in the Superior Colliculus and Lateral Geniculate Nucleus of Juvenile Rats Following Prenatal Exposure to Marijuana Smoke

open access: yesBasic and Clinical Neuroscience, 2021
Introduction: Prenatal exposure to Marijuana (MJN) has been associated with various brain deficits. The main activity in marijuana, Δ9-Tetrahydrocannabinol (THC), crosses the placenta and affects fetal brain development. Despite this, marijuana remains a
Grace Akingbade   +3 more
doaj  

Connecting the Brain to Itself through an Emulation. [PDF]

open access: yes, 2017
Pilot clinical trials of human patients implanted with devices that can chronically record and stimulate ensembles of hundreds to thousands of individual neurons offer the possibility of expanding the substrate of cognition.
Serruya, Mijail D.
core   +3 more sources

A Viral Labelling Study of Spinal Trigeminal Nucleus Caudalis Projection Neurons Targeting the Parabrachial Nucleus

open access: yesJournal of Neurochemistry, Volume 169, Issue 3, March 2025.
Using adeno‐associated viral vectors (AAVs) to label projection neurons (PN) that link nervous system regions is a powerful tool in neuroscience for studying circuitry and function. However, AAVs exhibit tropism, which can produce variable expression depending on the viral serotype and the CNS region targeted.
Sophie Maric   +4 more
wiley   +1 more source

A receptor-based analysis of local ecosystems in the human brain. [PDF]

open access: yes, 2017
BackgroundAs a complex system, the brain is a self-organizing entity that depends on local interactions among cells. Its regions (anatomically defined nuclei and areas) can be conceptualized as cellular ecosystems, but the similarity of their functional ...
Janušonis, Skirmantas
core   +1 more source

Phenotypic and Genotypic Characteristics of Adult‐Onset Glutaric Aciduria Type 1: Report of Two Cases and a Literature Review

open access: yesBrain and Behavior, Volume 15, Issue 2, February 2025.
This study reported two new cases and characterized the phenotype and genotype of adult‐onset glutaric aciduria Type 1 by literature review, emphasizing subependymal lesions and the coexistence of hyperhomocysteinemia. No clear genotype–phenotype correlation was found in adult‐onset glutaric aciduria Type 1. ABSTRACT Introduction Glutaric aciduria Type
Luhua Wei   +10 more
wiley   +1 more source

Locus Coeruleus Degeneration in Essential Tremor With Mild Cognitive Impairment: A Neuromelanin MRI Study

open access: yesCNS Neuroscience &Therapeutics, Volume 31, Issue 1, January 2025.
Using neuromelanin‐sensitive‐MRI (NM‐MRI) analysis, we found the integrity of locus coeruleus (LC) was decreased in ET patients and be more pronounced in ET‐MCI patients. The decreased integrity of LC was correlated with the severity of cognitive functions, suggesting some pathological changes of LC contribute to the cognitive impairment in ET ...
Yuelin Fang   +13 more
wiley   +1 more source

Delving into the significance of the His289Tyr single-nucleotide polymorphism in the glutamate ionotropic receptor kainate-1 (Grik1) gene of a genetically audiogenic seizure model

open access: yesFrontiers in Molecular Neuroscience
Genetic abnormalities affecting glutamate receptors are central to excitatory overload-driven neuronal mechanisms that culminate in seizures, making them pivotal targets in epilepsy research.
Sandra M. Díaz-Rodríguez   +10 more
doaj   +1 more source

The nature of the visual discrimination impairment after neonatal or adult ablation of superior colliculi in rats

open access: yesExperimental Brain Research, 1986
The superior colliculi were removed in rats at either one or five days of age or in adulthood. Seven months later they were tested on four successively presented two-choice intensity discriminations. The intensity difference between the discriminanda was reduced across the four problems to encourage choice by comparison.
Heywood, C, Cowey, A
openaire   +3 more sources

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