Results 91 to 100 of about 42,515 (269)

Intracerebroventricular insulin injection acutely normalizes the augmented exercise pressor reflex in male rats with type 2 diabetes mellitus

The Journal of Physiology, EarlyView.
Abstract figure legend The exercise pressor reflex (EPR), evoked by muscle contraction, is exaggerated in male rats with type 2 diabetes mellitus (T2DM). Cerebrospinal fluid insulin and phosphoinositide 3‐kinase in the nucleus tractus solitarius levels are normal in controls and low in T2DM rats, corresponding with normal and exaggerated EPR function ...
Juan A. Estrada, Rie Ishizawa, Han‐Kyul Kim, Ayumi Fukazawa, Amane Hori, Norio Hotta, Gary A. Iwamoto, Scott A. Smith, Wanpen Vongpatanasin, Masaki Mizuno   +9 more
wiley   +1 more source

GsMTx‐4 inhibits the exercise pressor reflex and the muscle mechanoreflex primarily through TRPC inhibition

The Journal of Physiology, EarlyView.
Abstract figure legend In decerebrated rats, injection of the TRPC6 channels antagonist (SAR7334) in the arterial supply of the triceps surae muscles was followed by injection of the TRPC6 and Piezo 2 channels antagonist (GsMTx‐4) to isolate the role of Piezo 2 in evoking the muscle mechanoreflex and exercise pressor reflex. The exercise pressor reflex
Guillaume P. Ducrocq, Laura Anselmi, Kristen Brandt, Jianli Wang, Victor Ruiz Velasco, Marc P. Kaufman   +5 more
wiley   +1 more source

Integration of auditory and visual communication information in the primate ventrolateral prefrontal cortex [PDF]

, 2006
The integration of auditory and visual stimuli is crucial for recognizing objects, communicating effectively, and navigating through our complex world.
Averbeck, BB, Diltz, MD, Romanski, LM, Sugihara, T   +3 more
core   +1 more source

VGLUT2 mRNA and protein expression in the visual thalamus and midbrain of prosimian galagos (Otolemur garnetti)

Eye and Brain, 2011
Pooja Balaram1, Toru Takahata1, Jon H Kaas1,21Department of Psychology, 2Department of Cell and Molecular Biology, Vanderbilt University, Nashville, TN, USAAbstract: Vesicular glutamate transporters (VGLUTs) control the storage and presynaptic release of
Pooja Balaram, Toru Takahata, Jon H Kaas
doaj  

Seeing without a Scene: Neurological Observations on the Origin and Function of the Dorsal Visual Stream

Journal of Intelligence
In all vertebrates, visual signals from each visual field project to the opposite midbrain tectum (called the superior colliculus in mammals). The tectum/colliculus computes visual salience to select targets for context-contingent visually guided ...
Robert D. Rafal
doaj   +1 more source

Expression of neuronal nitric oxide synthase in the developing superficial layers of the rat superior colliculus

Brazilian Journal of Medical and Biological Research, 2004
We investigated the level of expression of neuronal nitric oxide synthase (nNOS) in the retinorecipient layers of the rat superior colliculus during early postnatal development. Male and female Lister rats ranging in age between the day of birth (P0) and
A. Giraldi-Guimarães, R.E. Bittencourt-Navarrete, R. Mendez-Otero   +2 more
doaj   +1 more source

A High‐Fidelity RNA‐Targeting Cas13X Downregulates Connexin43 in Macroglia: A Novel Neuroprotective Strategy for Glaucoma

Advanced Science, Volume 12, Issue 33, September 4, 2025.
This study highlights the role of connexin43 (Cx43) in mediating glia activation and neuroinflammation in glaucoma. Using Cx43 knockout mice, it is shown that macroglial cells‐derived Cx43 modulates microglial activation, proliferation, migration, and polarization.
Guoli Zhao, Zhen Li, Ming‐Jie Zhao, Shu‐Ying Li, Qing Xia, Shuoyu Xu, Yu Zhang, Yi Wang, Fang Li, Yu‐Ling Liu, Yun‐Hui Guo, Ruo‐Xi Xu, Han Zhou, Hong Zhou, Wen‐Wen Ding, Yong‐Chen Wang, Yanying Miao, Zhongfeng Wang   +17 more
wiley   +1 more source

Distribution and characterisation of Glucagon-like peptide-1 receptor expressing cells in the mouse brain. [PDF]

, 2015
© 2015 The Authors.Objective: Although Glucagon-like peptide 1 is a key regulator of energy metabolism and food intake, the precise location of GLP-1 receptors and the physiological relevance of certain populations is debatable.
Cork, SC, Gribble, FM, Holt, MK, Reimann, F, Richards, JE, Trapp, S   +5 more
core   +2 more sources

Did Down‐Regulated Instincts Enable Human Gene‐Culture Coevolution?

Evolutionary Anthropology: Issues, News, and Reviews, Volume 34, Issue 3, September 2025.
ABSTRACT The unique intellectual and cultural attributes of Homo sapiens that arose during the Middle Stone Age are often ascribed to positive evolutionary development of novel physical or personality traits, but attempts to correlate cultural with genetic evolution have been unsuccessful.
Gerald E. Loeb
wiley   +1 more source

Temporal Interference Stimulation: Mechanisms, Optimization, Validation, and Clinical Prospects—A Comprehensive Review

WIREs Computational Statistics, Volume 17, Issue 3, September 2025.
This schematic highlights the key developments discussed in this review paper on Temporal Interference Stimulation (TIS), a non‐invasive technique for deep brain stimulation using interfering high‐frequency electric fields. Topics include optimization strategies, computational modelling, experimental findings, comparisons with other neuromodulation ...
Hossein Soroushi, Sara Abbasi, Yun Du, Ning Ning, Yuming Lei   +4 more
wiley   +1 more source