Results 71 to 80 of about 2,175,907 (298)

Impaired Auditory Temporal Selectivity in the Inferior Colliculus of Aged Mongolian Gerbils [PDF]

, 2011
Aged humans show severe difficulties in temporal auditory processing tasks (e.g., speech recognition in noise, low-frequency sound localization, gap detection). A degradation of auditory function with age is also evident in experimental animals.
Grothe, Benedikt, Khouri, Leila, Lesica, Nicholas A.   +2 more
core   +1 more source

Absence seizures: Update on signaling mechanisms and networks

Epilepsia Open, EarlyView.
Abstract Absence seizures (AS) are a hallmark of genetic generalized epilepsies (GGE), characterized by brief episodes of impaired consciousness accompanied by electroencephalographic spike‐and‐wave discharges (SWDs). Traditionally attributed to cortico‐thalamo‐cortical (CTC) dysrhythmia, emerging evidence suggests a more intricate pathophysiological ...
Ozlem Akman, Filiz Onat
wiley   +1 more source

Brainstem Alzheimer's-like pathology in the triple transgenic mouse model of Alzheimer's disease

Neurobiology of Disease, 2009
The triple transgenic mouse (3xTgAD), harboring human APPSwe, PS1M146V and TauP301L genes, develops age-dependent forebrain intraneuronal Aβ and tau as well as extraneuronal plaques.
Cassia R. Overk, Christy M. Kelley, Elliott J. Mufson   +2 more
doaj   +1 more source

Visual Function, Organization, and Development of the Mouse Superior Colliculus.

Annual Review of Vision Science, 2018
The superior colliculus (SC) is the most prominent visual center in mice. Studies over the past decade have greatly advanced our understanding of the function, organization, and development of the mouse SC, which has rapidly become a popular model in ...
Jianhua Cang, E. Savier, J. Barchini, Xiaorong Liu   +3 more
semanticscholar   +1 more source

Can We Talk About Fetal Consciousness?

Acta Paediatrica, EarlyView.
ABSTRACT Aim This mini‐review examines research on fetal consciousness, focusing on whether it can be empirically assessed or remains primarily a philosophical construct. Methods A review of theoretical frameworks was conducted. Behavioural evidence from studies of prenatal sensory responsiveness is evaluated, with particular attention to whether ...
Nadja Reissland
wiley   +1 more source

Detecting biological motion signals in human and monkey superior colliculus: a subcortical-cortical pathway for biological motion perception

Nature Communications
Most vertebrates, including humans, are highly adept at detecting and encoding biological motion, even when it is portrayed by just a few point lights attached to the head and major joints.
Xiqian Lu, Zhaoqi Hu, Yumeng Xin, Tianshu Yang, Ying Wang, Peng Zhang, Ning Liu, Yi Jiang   +7 more
doaj   +1 more source

Sensorimotor maps can be dynamically calibrated using an adaptive-filter model of the cerebellum.

PLoS Computational Biology, 2019
Substantial experimental evidence suggests the cerebellum is involved in calibrating sensorimotor maps. Consistent with this involvement is the well-known, but little understood, massive cerebellar projection to maps in the superior colliculus.
Emma D Wilson, Sean R Anderson, Paul Dean, John Porrill   +3 more
doaj   +1 more source

Superior Colliculus to VTA pathway controls orienting response and influences social interaction in mice

Nature Communications, 2022
Solié, Contestabile et al. show that the superior colliculus to ventral tegmental area (VTA) pathway encodes orienting behavior toward conspecifics, and modulates VTA dopamine neurons projecting onto dorsolateral striatum perturbing social interaction.
Clément Solié, Alessandro Contestabile, Pedro Espinosa, Stefano Musardo, Sebastiano Bariselli, Chieko Huber, Alan Carleton, Camilla Bellone   +7 more
doaj   +1 more source

Visual response properties of neurons in the superficial layers of the superior colliculus of awake mouse

Journal of Physiology, 2018
In rodents, including mice, the superior colliculus is the major target of the retina, but its visual response is not well characterized. In the present study, extracellular recordings from single nerve cells in the superficial layers of the superior ...
Gioia De Franceschi, S. Solomon
semanticscholar   +1 more source

Decoding neural responses to temporal cues for sound localization [PDF]

, 2013
The activity of sensory neural populations carries information about the environment. This may be extracted from neural activity using different strategies.
Aitkin, Ashida, Attwell, Brette, Briley, Carandini, Carlile, Casseday, Coles, Couchman, Couchman, Day, Dayan, Devore, Fischer, Fischer, Fitzpatrick, Fontaine, Furukawa, Glasberg, Goodman, Goodman, Gourévitch, Grothe, Hancock, Harper, Heffner, Heffner, Heffner, Heffner, Jeffress, Jenkins, Joris, Knudsen, Konishi, Kuenzel, Kuhn, Kuwada, Köppl, Lee, Lesica, Litovsky, Lüling, Maki, Makous, Malhotra, McAlpine, Miller, Moiseff, Moore, Pedregosa, Populin, Shera, Slaney, Sparks, Stecker, Sterbing, Stern, Takahashi, Thompson, Tollin, Tollin, Tollin, Wagner, Wakeford, Wightman, Yin, Yin, Yin   +68 more
core   +2 more sources