Results 51 to 60 of about 44,207 (262)

STRATEGIC TRANSFORMATIONS: INDIA'S PURSUIT OF COUNTERFORCE TARGETING AND REGIONAL STABILITY

Margalla Papers, 2023
In the intricate web of South Asia's security dynamics, India and Pakistan's relationship holds the key to equilibrium. Geographical proximity demands swift responses, prompting India's strategic shift towards Counterforce targeting.
Mubeen Ashraf , Syed Saif ul Haq
doaj  

Humor as a threat-coding mechanism

The European Journal of Humour Research, 2020
The integration of humour’s classical theories such as relief, superiority, and incongruity suggest that the differences and patterns in what we find funny are largely dependent on attaching an “explicably safe” meaning to novel entities.
Edward Greenberg
doaj   +1 more source

Saccade Target Selection in the Superior Colliculus: A Signal Detection Theory Approach [PDF]

The Journal of Neuroscience, 2008
How the brain selects one action from among multiple options is unknown. A main tenet of signal detection theory (SDT) is that sensory stimuli are represented as noisy information channels. Therefore, the accuracy of selection might be predicted by how well neuronal activity representing alternatives can be distinguished.
Byounghoon, Kim, Michele A, Basso
openaire   +2 more sources

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

A new correlation belief function in Dempster-Shafer evidence theory and its application in classification

Scientific Reports, 2023
Uncertain information processing is a key problem in classification. Dempster-Shafer evidence theory (D-S evidence theory) is widely used in uncertain information modelling and fusion.
Yongchuan Tang, Xu Zhang, Ying Zhou, Yubo Huang, Deyun Zhou   +4 more
doaj   +1 more source

Problem Structures in the Theory and Practice of Superiorization

, 2019
The purpose of this short paper is to identify the mathematical essence of the superiorization methodology. This methodology has been developed in recent years while attempting to solve specific application-oriented problems. Consequently, superiorization is often presented using the terminology of such problems.
openaire   +2 more sources

Clinical Spectrum and Outcomes of SOX1 Antibody‐Associated Paraneoplastic Neurological Syndromes: A Chinese Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background SOX1 antibody‐positive paraneoplastic neurological syndromes (PNS) exhibit significant population‐specific clinical heterogeneity. While Western cohorts predominantly manifest Lambert‐Eaton myasthenic syndrome (65%–80%), comprehensive clinical characterization and treatment response data in Asian populations remain critically ...
Jin‐Long Ye, Zu‐Ying Kuang, Bo Li, Meng‐Qiu Pan, Li‐Hua Zhou, Yang‐Yang Dai, Si‐Fen Xie, Xian‐Guang Lin, Ye‐Peng Hu, Li‐Hong Jiang, Zhan‐Hang Wang, Wei‐Jing Zhang   +11 more
wiley   +1 more source

Transformation properties of the Lagrange function

Revista Brasileira de Ensino de Física
In the context of the Lagrangian and Hamiltonian mechanics, a generalized theory of coordinate transformations is analyzed. On the basis of such theory, a misconception concerning the superiority of the Hamiltonian formalism with respect to the ...
Carlo Ferrario, Arianna Passerini
doaj   +1 more source