Results 191 to 200 of about 254,793 (268)

Cardiovascular toxicity from immune checkpoint inhibitor therapy: an inflammatory continuum

open access: yesBritish Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitor (ICI) therapy has markedly improved outcomes in advanced malignancies but has also revealed a distinct spectrum of cardiovascular immune‐related adverse events. Myocarditis represents the most severe manifestation, while non‐inflammatory left ventricular dysfunction and vascular inflammation have emerged as additional ...
Fabrice Reyes   +7 more
wiley   +1 more source

A CECT‐Based 2PI System as a Novel Noninvasive Prognostic Tool for Hepatocellular Carcinoma: A Dual‐Validation Study

open access: yesCancer Science, EarlyView.
Using differential weighting, we developed a 2PI‐based risk stratification system for HCC recurrence. A comprehensive prognostic model incorporating clinical variables and the 2PI score further enhanced postoperative prediction in solitary HCC and showed initial generalizability across SR and RFA cohorts.
Yingzhu Cui   +10 more
wiley   +1 more source

Exploring the Neural Pathways of Faith: A Review and Case Study on Hyperreligiosity in Epilepsy. [PDF]

open access: yesNeuroSci
Bazarra Castro GJ   +6 more
europepmc   +1 more source

Integrated Transcriptomics of Human and Canine Osteosarcoma Reveals Species Stemness and Trabectedin Sensitivity

open access: yesCancer Science, EarlyView.
Comprehensive comparative molecular framework for human and canine osteosarcomas. Integrated transcriptomic analyses establish a comprehensive comparative molecular framework for human and canine osteosarcomas. By defining species‐specific stemness architectures and drug response dynamics, our findings highlight the necessity of accounting for distinct
Kenta Kono   +7 more
wiley   +1 more source

Tryptase Locus Variation Contributes to Normal‐Range Basal Serum Tryptase Variability and Is Associated With Anaphylaxis

open access: yesClinical &Experimental Allergy, EarlyView.
Tryptase locus variation explains normal‐range baseline serum tryptase differences and is associated with Hymenoptera venom anaphylaxis, independent of clonal mast cell disease and HαT. ABSTRACT Background Increased basal serum tryptase level (BST) is associated with anaphylaxis.
Manca Svetina   +6 more
wiley   +1 more source

Quality of life, stigma, and mental health, in individuals affected by leprosy: a cross-sectional study. [PDF]

open access: yesTrans R Soc Trop Med Hyg
Chala TK   +4 more
europepmc   +1 more source

Premium Intraocular Lens Selection in Patients With Glaucoma: A Clinical Review

open access: yesClinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Glaucoma frequently coexists with cataract, but glaucomatous functional loss, ocular‐surface disease, anatomical abnormalities, and treatment‐related refractive variability may reduce tolerance of premium intraocular lenses. This narrative review critically appraises evidence relevant to lens selection in glaucoma. Central visual‐field status,
Zhihao Liu   +3 more
wiley   +1 more source

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