A Post–NGP Mitsuokella jalaludinii as a Therapeutic Candidate for Gout
Schematic summary of the therapeutic mechanisms and evaluation of the post–NGP strain M. jalaludinii PMC73 for gout. PMC73 demonstrated uric acid–lowering efficacy through purine catabolism and hypoxanthine utilization, along with intracellular uric acid reduction in macrophages.
Mohammed Solayman Hossain +13 more
wiley +1 more source
Intratumoral Microbiota in Fueling Cancer and Steering Treatment Response
Emerging research underscores the tumor‐specific colonization of microbiota and the role of intratumoral microbiota in cancer development and treatment resistance across multiple malignancies. Here, we provide a systematic review exploring the latest biotechnological advancements for studying low‐abundance intratumoral microbiota, their origins ...
Minhui Xu +7 more
wiley +1 more source
Genetic dosage and position effect of small supernumerary marker chromosome (sSMC) in human sperm nuclei in infertile male patient. [PDF]
Olszewska M +9 more
europepmc +1 more source
Metabolization of Flavan‐3‐ol Oligomers by Eggerthella lenta, a Human Gut Bacterium
Novel human gut bacterial strains were isolated and characterized for their ability to metabolize flavan‐3‐ols. While Eggerthella lenta and Flavonifractor plautii metabolized flavan‐3‐ol monomers, only E. lenta converted B‐ and A‐type procyanidins, demonstrating that this gut bacterium can metabolize flavan‐3‐ol oligomers.
Ruben Halifa +10 more
wiley +1 more source
Dual localization of PDI5 couples endoplasmic reticulum proteostasis to meristem organization and meiotic fidelity in Arabidopsis. [PDF]
Aslam M +4 more
europepmc +1 more source
A New Case of a Complex Small Supernumerary Marker Chromosome: A Der(9)t(7;9)(p22;q22) due to a Maternal Balanced Rearrangement. [PDF]
Manvelyan M +5 more
europepmc +1 more source
Abstract Reliable detection of structural variants (SVs) and copy number variations (CNVs) is crucial in the contemporary diagnostics of pediatric B‐cell acute lymphoblastic leukemia (B‐ALL). However, limitations of commonly used conventional and molecular cytogenetic methods may hinder the accurate genetic characterization of patients.
Anna Bekő +21 more
wiley +1 more source
Centromeric instability and chromoanasynthesis observed in nine supernumerary marker chromosomes resolved with long-read genome sequencing. [PDF]
Bilgrav Saether K +8 more
europepmc +1 more source
Molecular characterization of an analphoid supernumerary marker chromosome derived from 18q22.1➔qter in prenatal diagnosis: a case report. [PDF]
Altieri V +6 more
europepmc +1 more source

