Results 321 to 330 of about 402,173 (377)

Effect of Aluminium on Superoxide Dismutase

Clinical Science, 1989
1. The effect of Al3+ on superoxide dismutase in vitro was studied, since in uraemia there is excessive superoxide production and frequently an elevated serum Al3+ level. Thus, the protective role of superoxide dismutase is particularly important. 2.
Geoffrey M. Berlyne, Ruth Shainkin-Kestenbaum, C. Caruso, Andrew J. Adler   +3 more
openaire   +3 more sources

Effect of aluminium on lipid peroxidation, superoxide dismutase, catalase, and peroxidase activities in root tips of soybean (Glycine max)

, 1991
Inhibition of root elongation and modification of membrane properties are sensitive responses of plants to aluminium. The present paper reports on the effect of AI on lipid peroxidation and activities of enzymes related to production of activated oxygen ...
I. Cakmak, W. Horst
semanticscholar   +1 more source

Extension of life-span by overexpression of superoxide dismutase and catalase in Drosophila melanogaster.

Science, 1994
The hypothesis that oxygen free radicals are causally involved in the aging process was tested by a study of the effects of simultaneous overexpression of copper-zinc superoxide dismutase and catalase.
W. Orr, R. S. Sohal
semanticscholar   +1 more source

Bacterial Superoxide Dismutases

1988
Superoxide dismutase (SOD) has played a major role in establishing the biological relevance of oxyradicals. To many oxyradical researchers, “superoxide dismutase” connotes a copper-zinc SOD (CuZnSOD), the first dismutase to be purified and the form of prime interest clinically. However, superoxide dismutases containing manganese or iron as cofactor are
openaire   +3 more sources

Amyotrophic lateral sclerosis and structural defects in Cu,Zn superoxide dismutase.

Science, 1993
Single-site mutants in the Cu,Zn superoxide dismutase (SOD) gene (SOD1) occur in patients with the fatal neurodegenerative disorder familial amyotrophic lateral sclerosis (FALS).
H. Deng, A. Hentati, J. Tainer, Zafar Iqbal, A. Cayabyab, W. Hung, E. Getzoff, Ping Hu, B. Herzfeldt, R. Roos, C. Warner, Gang Deng, Edwin Soriano, C. Smyth, H. Parge, Aftab Ahmed, A. Roses, R. Hallewell, M. Pericak-Vance, T. Siddique   +19 more
semanticscholar   +1 more source

Superoxide Dismutase in Epidermis (1)

The Journal of Dermatology, 1987
AbstractSuperoxide dismutase (SOD), which catalytically scavenges superoxide anion (O–2), constitutes an essential defense against the toxicity of oxygen. We investigated the enzyme activity of pig skin epidermis. SOD activity was determined by monitoring the inhibitory effect of SOD on red formazan formation from neotetrazolium, which depends on (O–2)
Akira Ohkawara, Hajime Iizuka, Noritaka Ohkuma, Shinobu Matsuo   +3 more
openaire   +3 more sources

Mimics of Superoxide Dismutase

2019
Chemists have attempted to mimic such enzymes as P450s, catalases, hemoglobin, photosynthetic reaction centers, and superoxide dismutases to name a few. An ideal mimic would catalyze the same reaction as the parent enzyme with specificity and efficiency matching that of the native enzyme. Several criteria determine which synthetic compounds will be the
Fridovich Irwin, M. Faulkner Kevin
openaire   +2 more sources

Superoxide dismutases in chronic gastritis

APMIS, 2016
Human gastric diseases have shown significant changes in the activity and expression of superoxide dismutase (SOD) isoforms. The aim of this study was to detect Mn‐SOD activity and expression in the tissue of gastric mucosa, primarily in chronic gastritis (immunohistochemical Helicobacter pylori‐negative gastritis, without other pathohistological ...
Dražen Švagelj, Marija Švagelj, Velimir Terzić, Mirta Cvrković, Ivan Švagelj, Jasna Dovhanj   +5 more
openaire   +3 more sources

Reversal of the superoxide dismutase reaction

Biochemical and Biophysical Research Communications, 1973
Abstract The superoxide dismutase from bovine erythrocytes has been shown to catalyze the reduction of oxygen by H2O2. This reversal of the spontaneous disproportionation of superoxide radicals was made feasible through the use of tetranitromethane as an effective scavenger for the superoxide radicals.
Irwin Fridovich, Ellen K. Hodgson
openaire   +3 more sources

Superoxide, superoxide dismutase and ischemic injury.

Current opinion in investigational drugs (London, England : 2000), 2002
Oxidative stress results from an oxidant/antioxidant imbalance: an excess of oxidants relative to the antioxidant capacity. Recent evidence strongly suggests that oxidant stress plays a major role in several aspects of ischemia and reperfusion. Immunohistochemical and biochemical evidence demonstrate the significant role of reactive oxygen species, in ...
Salvemini, Daniela, CUZZOCREA, Salvatore
openaire   +2 more sources