Results 41 to 50 of about 137,621 (290)

Numerical Analysis of Aerodynamic Interference of Two Passing Cylindrical Bodies at Supersonic Speeds [PDF]

مکانیک هوافضا, 2023
Aerodynamic interference is one of the phenomena that occurs when two flying objects pass near each other. In this case, the change in the pressure distribution on objects passing near each other causes a change in the aerodynamic forces.
Mohammad Ali Ranjbar, Alireza Pourmoayed, Sina Alimohammadian   +2 more
doaj  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Multifidelity Comparison of Supersonic Wave Drag Prediction Methods Using Axisymmetric Bodies

Aerospace
Low-fidelity analytic and computational wave drag prediction methods assume linear aerodynamics and small perturbations to the flow. Hence, these methods are typically accurate for only very slender geometries.
Troy Abraham, David Lazzara, Douglas Hunsaker   +2 more
doaj   +1 more source

Aerodynamic Optimization Design of Supersonic Wing Based on Discrete Adjoint

Aerospace, 2023
Reducing fuel consumption and improving the economy by effectively reducing cruising drag is the main objective of the aerodynamic design of supersonic civil aircraft.
Hanyue Rao, Yayun Shi, Junqiang Bai, Yifu Chen, Tihao Yang, Junfu Li   +5 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Numerical Study on the Influence of Suction near Expansion Corner on Separation Bubble

Aerospace
Suction is an important control method in the shock wave and boundary layer interaction (SWBLI). Aimed at the problem of separation bubbles induced at the expansion corners, this study investigates the influence of suction on both the dimensions of ...
Yaowen Zhang, Shaozhan Wang, Dangguo Yang, Bin Dong   +3 more
doaj   +1 more source

Supersonic Combustion Modeling and Simulation on General Platforms

Aerospace, 2022
Supersonic combustion is an advanced technology for the next generation of aerospace vehicles. In the last two decades, numerical simulation has been widely used for the investigation on supersonic combustion.
Shizhuo Huang, Qian Chen, Yuwei Cheng, Jinyu Xian, Zhengqi Tai   +4 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

FEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso, Jaime Hiniesta‐Valero, Alejandra Guerra‐Castellano, Miguel A. De la Rosa, Irene Díaz‐Moreno   +4 more
wiley   +1 more source

Study on Flow Characteristic of Sub-/Super-Sonic Mixing Layer

Xibei Gongye Daxue Xuebao, 2020
In order to obtain the flow characteristics of sub-super-sonic mixing layer including velocity distribution, pressure distribution and development of mixing layer, experimental and numerical investigations were conducted.

doaj   +1 more source