Results 61 to 70 of about 62,597 (240)

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

Molecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau, Daniel Pincher, Clifford Young, Nicholas Chappell, Noor A. Lokman, Parul Mittal, Leigh Donnellan, Martin K. Oehler, Doug A. Brooks, Peter Hoffmann   +9 more
wiley   +1 more source

Shock induced fluid structure interaction on a flexible wall in supersonic turbulent flow [PDF]

, 2011
A detailed knowledge of the flow structure interaction in supersonic flows is important for the design of future space transportation systems. Therefore this work was devoted to the investigation of the shock wave boundary layer interaction on an ...
Esser, Burkard, Gülhan, Ali, Willems, Sebastian   +2 more
core  

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

High-Speed Aircraft Stability and Control Metrics

Aerospace
This review paper identifies key stability and control screening parameters needed to design low-risk, general-purpose high-speed aircraft. These derive from MIL-STD-8785C, MIL-STD-1797, and older AGARD reports, and are suitable for assessing conceptual ...
Timothy T. Takahashi, Jack A. Griffin, Ramana V. Grandhi   +2 more
doaj   +1 more source

Component Analysis of TBCC Propulsion for a Mach 4.5 Supersonic Cruise Airliner [PDF]

, 2007
This paper describes the status of the study on component analysis for the different Variable TBCC cycle configurations. The paper investigates different Variable Cycle TBCC configurations and compares them with an advanced turbojet for the generic ...
Okai, Keiichi, Sippel, Martin
core  

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Supersonic Waves Generated by the 18 November 2023 Starship Flight and Explosions: Unexpected Northward Propagation and a Man‐Made Non‐chemical Depletion

Geophysical Research Letters
On 18 November 2023, SpaceX launched the Starship, the tallest and the most powerful rocket ever built. The Super Heavy engine separated from the Starship spacecraft and exploded at 90 km of altitude, while the main core Starship continued to rise up to ...
Y. V. Yasyukevich, A. M. Vesnin, E. Astafyeva, B. M. Maletckii, V. P. Lebedev, A. M. Padokhin   +5 more
doaj   +1 more source

Comparison of Prediction Models for Sonic Boom Ground Signatures Under Realistic Flight Conditions

Aerospace
This paper presents a comparative analysis of simplified and high-fidelity sonic boom prediction methods to assess their applicability in the conceptual design of supersonic aircraft. The high-fidelity approach combines Computational Fluid Dynamics (CFD)
Jacob Jäschke, Samuele Graziani, Francesco Petrosino, Antimo Glorioso, Volker Gollnick   +4 more
doaj   +1 more source

A Low Psoas Muscle Index Was Associated With a Poorer Overall Survival in Patients Who Underwent Percutaneous Nephrostomy

Aging and Cancer, EarlyView.
In patients with malignant ureteral obstruction undergoing percutaneous nephrostomy, sarcopenia defined by a low psoas muscle index was independently associated with poor overall survival on multivariate Cox regression analysis, suggesting that preoperative assessment of psoas muscle index may aid prognostic stratification in this population.
Kota Shimokihara, Takashi Kawahara, Kazuhide Makiyama, Hiroji Uemura   +3 more
wiley   +1 more source

A Novel, Direct Matrix Solver for Supersonic Boundary Element Method Systems

Aerospace
For problems with very fine surface meshes, typically the most time-consuming step of a boundary element method (BEM, also called a panel method) is solving the final linear system of equations.
Cory Goates, Douglas Hunsaker
doaj   +1 more source