Results 41 to 50 of about 138,816 (307)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Numerical Analysis of Aerodynamic Interference of Two Passing Cylindrical Bodies at Supersonic Speeds [PDF]

open access: yesمکانیک هوافضا, 2023
Aerodynamic interference is one of the phenomena that occurs when two flying objects pass near each other. In this case, the change in the pressure distribution on objects passing near each other causes a change in the aerodynamic forces.
Mohammad Ali Ranjbar   +2 more
doaj  

Structure Function Scaling of a 2MASS Extinction Map of Taurus [PDF]

open access: yes, 2002
We compute the structure function scaling of a 2MASS extinction map of the Taurus molecular cloud complex. The scaling exponents of the structure functions of the extinction map follow the Boldyrev's velocity structure function scaling of supersonic ...
Boldyrev S.   +6 more
core   +3 more sources

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Multifidelity Comparison of Supersonic Wave Drag Prediction Methods Using Axisymmetric Bodies

open access: yesAerospace
Low-fidelity analytic and computational wave drag prediction methods assume linear aerodynamics and small perturbations to the flow. Hence, these methods are typically accurate for only very slender geometries.
Troy Abraham   +2 more
doaj   +1 more source

Aerodynamic Optimization Design of Supersonic Wing Based on Discrete Adjoint

open access: yesAerospace, 2023
Reducing fuel consumption and improving the economy by effectively reducing cruising drag is the main objective of the aerodynamic design of supersonic civil aircraft.
Hanyue Rao   +5 more
doaj   +1 more source

On the Existence of Shocks in Irradiated Exoplanetary Atmospheres

open access: yes, 2012
Supersonic flows are expected to exist in the atmospheres of irradiated exoplanets, but the question of whether shocks develop lingers. Specifically, it reduces to whether continuous flow in a closed loop may become supersonic and if some portions of the
Heng, Kevin
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Numerical Study on the Influence of Suction near Expansion Corner on Separation Bubble

open access: yesAerospace
Suction is an important control method in the shock wave and boundary layer interaction (SWBLI). Aimed at the problem of separation bubbles induced at the expansion corners, this study investigates the influence of suction on both the dimensions of ...
Yaowen Zhang   +3 more
doaj   +1 more source

Supersonic Combustion Modeling and Simulation on General Platforms

open access: yesAerospace, 2022
Supersonic combustion is an advanced technology for the next generation of aerospace vehicles. In the last two decades, numerical simulation has been widely used for the investigation on supersonic combustion.
Shizhuo Huang   +4 more
doaj   +1 more source

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