Results 101 to 110 of about 2,063,309 (209)

Avances en supervisión educativa

open access: yes, 2011
Resumen basado en el de la publicaciónResumen también en inglésLa implantación de nuevas políticas y programas educativos, como la enseñanza bilingüe, en un conjunto considerable de centros, debería conllevar la evaluación de los mismos, y especialmente ...
Borderías Clau, Reyes
core  

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

La supervisión educativa en nuestro país: El trabajo del supervisor en cinco jurisdicciones

open access: yes, 2013
En las últimas décadas, en la mayoría de los países se han implementado políticas que resignifican el trabajo del supervisor poniendo un mayor énfasis en las tareas relacionadas con el apoyo, el asesoramiento, y el acompañamiento a las escuelas y los ...
Hirschberg, Sonia   +12 more
core  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Supervisión, evaluación y calidad educativa

open access: yes, 2005
oai:ojs.pkp.sfu.ca:article/2La autora hace un recorrido por las funciones habituales de la inspección que concreta en informar, asesorar, mediar, controlar y evaluar y que engloba bajo la denominación de supervisión educativa haciendo sinónimos los ...
Casanova, Mª Antonia
core  

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

La Revista Especializada Acción y Reflexión Educativa: 38 años de trayectoria al servicio de la educación panameña.

open access: yesAcción y Reflexión Educativa, 2016
Este escrito presenta, de manera muy general, la génesis y la evolución de la Revista Especializada Acción y Reflexión Educativa que publica, desde 1978, el Instituto Centroamericano de Administración y Supervisión de la Educación (ICASE) de la ...
Magda Lida Jurado
doaj  

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

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