Results 121 to 130 of about 2,396,272 (238)
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Management scope model design, time and cost of supervision field area as a telecommunications company projects methodology guidelines PMI V5 [PDF]
, 2016 El presente trabajo tiene com propósito la formulación de una metodología de gestión de proyectos del área de supervisión de actividades de campo de una empresa de telecomunicaciones, tomando los lineamientos para la gestión de proyecto PMI.
Hernández Caicedo, Jorge Armando
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Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Scientific ReportsThe use of amendments in combination with Bacillus subtilis has been understudied as a strategy for rehabilitating acid soils and improving cropping systems. This study aimed to evaluate the effects of amendments and B. subtilis on the development, yield,
Henry Diaz-Chuquizuta +7 more
doaj +1 more source
El autoconocimiento en el espacio de la supervisión educativa, en los estudios de trabajo social de la Universidad de Barcelona [PDF]
, 2017 Projecte: 2015PID-UB/026Esta comunicación aborda el autoconocimiento del alumnado en el Grado de Trabajo Social de la Universidad de Barcelona. Concretamente, se presentan los resultados y conclusiones acerca del ejercicio de autoconocimiento realizado ...
Boixadòs, Adela +4 more
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Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Control Interno : Aplicación del control interno basado en el informe COSO en el área de compras de materiales y suministros de la empresa Mariscos de Nicaragua,S.A. Durante el primer semestre 2015 [PDF]
, 2016 La presente investigación tiene como objetivo general, analizar la aplicación del Control Interno basado en el informe COSO II, en el área de compras de materiales y suministros de la empresa Mariscos de Nicaragua, S.A. durante el primer semestre 2015.
Reyes Salgado, Yirlani Cristabel +1 more
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Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source