Results 121 to 130 of about 2,351,817 (237)
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Validando buenas prácticas en la docencia de Trabajo Social: en el camino de la innovación didáctica [PDF]
, 2016 Durante el curso pasado, la red REDITS avanzó en la identificación de diversas estrategias para mejorar la adquisición de competencias que quedaron volcadas en la memoria del proyecto desarrollado. Siguiendo con el trabajo iniciado, la red se propuso una
Ariño Antuna, Miren +6 more
core
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Scientific ReportsThe use of amendments in combination with Bacillus subtilis has been understudied as a strategy for rehabilitating acid soils and improving cropping systems. This study aimed to evaluate the effects of amendments and B. subtilis on the development, yield,
Henry Diaz-Chuquizuta +7 more
doaj +1 more source
Supervisión de la simulación de procesos de control mediante ecuaciones de paridad FF [PDF]
, 2003 [Resumen] Este artículo describe la tarea de supervisión del proceso de simulación en tiempo real de procesos de control. El algoritmo propuesto de supervisión del proceso de simulación está basado en el procesamiento masivamente paralelo de ecuaciones
Ferreiro García, Ramón +1 more
core
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Grado de supervisión entre liderazgo y satisfacción del personal ejecutivo comercial del Banco Falabella Open Plaza Chiclayo [PDF]
, 2017 La presente investigación se desarrolla sobre la Empresa Banco Falabella Chiclayo, específicamente en la sucursal Open Plaza. La investigación nace a partir de la intención de medir la satisfacción laboral de los encargados de la parte comercial del ...
Moncayo Ylma, Claudia Paola +1 more
core +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source