Results 161 to 170 of about 2,351,817 (237)

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

Authors' response to letter to the Editor from Aphale, P, et al., Resident autonomy in pathology: bridging gaps between training and practice. [PDF]

Acad Pathol
Bryant BH, Puligandla B, Gosnell HL, Johnson K, Barak S, Berg MP, Karp JK, Lofgreen A, McCloskey CB, Knollmann-Ritschel BEC, White KL, Black-Schaffer WS.   +11 more
europepmc   +1 more source

Sustainable bioplastics manufacturing from renewable sources

FEBS Open Bio, EarlyView.
Bioplastics are manufactured by using polymers from different bio‐based sources. These novel materials not only offer biodegradability but also possess various functional properties that make them suitable for diverse applications. Recent developments in the preparation of bioplastics are reported, highlighting the distinct properties of each type of ...
C. Valeria L. Giosafatto, Marika Avitabile, Michela Famiglietti, Talayeh Kordjazi, Marzieh Moosavi‐Nasab, Odile F. Restaino, Loredana Mariniello   +6 more
wiley   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source

Real-world outcomes of trastuzumab deruxtecan in patients with HER2+ metastatic breast cancer: Turkish oncology group multicenter study. [PDF]

Ther Adv Med Oncol
Sahin TK, Kemik F, Muglu H, Acikgöz Yildiz B, Biter S, Tunbekici S, Oruc A, Guren AK, Kaban K, Guzel HG, Erol C, Aykan MB, Koylu B, Ekinci OB, Deliktas Onur I, Kalem A, Altunok O, Seyyar M, Guney B, Akdogan O, Ismayilov R, Ardic FS, Yazici M, Majidova N, Turker S, Esin E, Cabuk D, Yasar HA, Oguz A, Yazici O, Gursu RU, Yılmaz M, Yesil Cinkir H, Ates O, Celik E, Karadurmus N, Demirci U, Ozturk B, Mandel NM, Bayoglu IV, Araz M, Goker E, Bayram E, Erdem D, Selcukbiricik F, Basaran G, Sezer A, Dogu GG, Kemal Y, Bilici A, Gunduz S, Guven DC, Aksoy S.   +52 more
europepmc   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Effect of Pharmacy Student Peer Supervision on the Accuracy of Admission Medication Reconciliation: Prospective Pre-Post Observational Study.

JMIR Hum Factors
Ammor B, Masse M, Toulemonde A, Cadart L, Beuscart JB, Lambert M, Odou P, Décaudin B.   +7 more
europepmc   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

FEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc, Blaž Stres, Mirica Karlovits, Igor Karlovits, Petra Jerič, Ondrej Panák, Anja Verbič, Blaž Likozar, Uroš Novak   +8 more
wiley   +1 more source

Too much synchrony? Left bundle branch area pacing-induced systolic anterior motion and left ventricular outflow tract obstruction managed by intentional atrioventricular dyssynchrony. [PDF]

Korean J Intern Med
Jeong HK, Kim SS, Kim HK, Ki YJ, Choi DH, Park KH.   +5 more
europepmc   +1 more source