Results 71 to 80 of about 2,239,240 (303)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Veranstaltung

Forum Supervision, 2022
Forum Supervision - Masterbüro „Supervision und Beratung"
doaj   +1 more source

Towards effective practice in offender supervision

, 2009
This paper has been prepared principally for the Performance Improvement Strategy Group - a group convened by the Community Justice Division of the Scottish Government to advise and assist in the development of criminal justice social work services in ...
McNeill, Fergus, Scottish Centre for Crime and Justice Research (Funder), , Scottish Centre for Crime and Justice Research (Funder)   +2 more
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Veranstaltung

Forum Supervision, 2023
Forum Supervision - Masterbüro „Supervision und Beratung"
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Autor_innenverzeichnis

Forum Supervision, 2020
Forum Supervision
doaj   +1 more source

Group supervision from a small group perspective

, 2006
The main objective of this study was to examine a set of independent group variables (group size, gender composition, and supervisory style) in group supervision, and their interrelation with supervisees’ and supervisors’ view on group interactions ...
Boalt Boëthius, S, Ögren, M-L, Sundin, EC   +2 more
core  

Berufliche Identität und Supervision bei PhysiotherapeutInnen.

, 2006
Supervision findet meistens in „Feldern“ statt, z.B. im Feld des Krankenhauses, Rehabilitationszentrums, der Psychiatrie usw. Diese Felder gehören zu den Kontextfaktoren der Supervision und haben jeweils spezifische unterschiedliche Traditionen ...
Wijnen, Hester van
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source