Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Student-supervisor-university expectation alignment in the undergraduate engineering thesis
Given the lack of student research experience, the undergraduate thesis is necessarily focussed primarily on development of research skills (i.e. it is process oriented). Since postgraduate supervision is research output focussed, the lessons learnt from
Brad Stappenbelt (19585081) +1 more
core +1 more source
On becoming a supervisor: an anticipated transition for trainee clinical psychologists [PDF]
Section A reviews the empirical and theoretical literature on supervision in order to gain a better understanding of how experiences of supervision during clinical training may relate to the anticipated transition of ‘becoming a supervisor’.
Peacock, E.
core
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Supervisor social skill and supervision outcome
Background: The practice of clinical supervision is considered an effective procedure to achieve a variety of professional outcomes for supervisees. Supervisory alliance mediates many of the learning outcomes thought important for effective supervision ...
Bambling, Matthew, King, Robert
core +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Optimizer Algorithms for Supervisory Control : Enabling Supervisor Input:(SUPEROPT D2) [PDF]
This document reports the methods developed by the SUPEROPT project for supervisor interaction with optimizers. Two mathematical forms for an optimizer to support a Multi-Sector Controller are presented and compared, including various constraint forms to
Richards, Arthur G, Turnbull, Oliver D N
core
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
The Effects of Supervisor-Subordinate Genders on Subordinates’ Involvement Across Managerial Functions [PDF]
One of the renowned agendas’ of the management study around the globe encircles the gender biasness or non-biasness in performing the basic managerial functions.
Subhani, Muhammad Imtiaz +1 more
core
Discerning protein pools by selective staining with self‐labeling tags
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source

