Results 101 to 110 of about 124,234 (346)

Information Externality, Bank Structure, and Economy

open access: yesKDI Journal of Economic Policy, 2005
This paper addresses the question of whether a monopolistic banking system can lead to a higher steady state level of capital stock. Information externality has enhanced as the advance of the financial system such as the establishment of the credit ...
Doh, Bo-Eun
doaj   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

open access: yesMolecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova   +18 more
wiley   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

Landscape of BRAF transcript variants in human cancer

open access: yesMolecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda   +5 more
wiley   +1 more source

Mediação e acompanhamento na formação, educação e desenvolvimento profissional Mediación y acompañamiento en la formación educación e desarrollo profesional Mediating and monitoring training, education and professional development

open access: yesRevista de Enfermagem Referência, 2012
As políticas de educação e ensino superior reconhecem a importância da aprendizagem mediada, no complexo processo de desenvolvimento da cadeia educativa: da gestão da informação à construção de conhecimento e sabedoria para agir.
Manuel Alves Rodrigues   +1 more
doaj  

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

open access: yesMolecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh   +8 more
wiley   +1 more source

TRPM8 levels determine tumor vulnerability to channel agonists

open access: yesMolecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo   +18 more
wiley   +1 more source

The relationship of communication skills with leadership style and conflict management strategies of head nurses: A cross-sectional study in Northern Iran [PDF]

open access: yesJournal of Research Development in Nursing and Midwifery
Background: Head nurses, as operational managers of hospitals, require robust communication skills, comprehensive leadership knowledge, and proficient conflict management strategies.
Alireza Heidari   +8 more
doaj  

ANALYSIS OF RISK-BASED ASSET MANAGEMENT PLAN TO INCREASE PERFORMANCE OF WATER LOCAL COMPANY

open access: yesJurnal Bisnis dan Manajemen, 2019
This study aims to obtain the concept of risk-based asset management planning with consideration of government regulations and international standards of asset management that can improve the performance of Regional Water Company (PDAM) of Aceh Province.
Monita Mardika Fajar   +2 more
doaj   +1 more source

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