Results 101 to 110 of about 127,847 (301)

Market newsletter 2/2015 [PDF]

open access: yes, 2015
Topical matters at ESMA 1 Changes to the periodic disclosure obligation and availability of information – Entry into force on 26 November 2015 2 Significant changes in the obligation to notify of changes in major shareholdings as from 26 November 2015 ...

core  

FDI Flows in Balkans: What is Contributing to this Important Pillar for Growth?

open access: yesEIRP Proceedings, 2023
Many countries in the Balkan region have long been awaiting their accession in the European Union. Countless efforts, governmental reforms and policies are undertaken to ensure compliance with the international standards, adoption of best practices and
Egis Zaimaj
doaj  

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Modular synthesis of discrete controllers [PDF]

open access: yes, 2007
This paper presents supervisory control theory in a process-algebraic setting, and proposes a way of synthesising modular supervisors that guarantee nonblocking.
Reeves, Steve   +7 more
core   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

National Banking Law in the European Single Supervisory Mechanism

open access: yes, 2020
In 2013, the European Central Bank acquired the competence to apply national banking law in a direct manner to banks established in the euro area, as part of its supervisory competence under the Single Supervisory Mechanism. This marks the first instance
VOORDECKERS, Olivier
core   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Market newsletter 1/2024 [PDF]

open access: yes
In this article, we outline the main features of market supervision in 2023, what we focused on in prospectus and takeover bid supervision, disclosure obligation supervision and monitoring of securities market trading, and what we will focus on in these ...

core  

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

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