Results 11 to 20 of about 143,032 (186)

Phase I/II study of adding intraperitoneal paclitaxel in patients with pancreatic cancer and peritoneal metastasis

BJS (British Journal of Surgery), Volume 107, Issue 13, Page 1811-1817, December 2020., 2020
This multicentre phase I/II study was undertaken to determine the recommended dose of the combination of intravenous gemcitabine, intravenous nab‐paclitaxel and intraperitoneal paclitaxel in patients with pancreatic ductal adenocarcinoma and peritoneal metastasis, and to evaluate its clinical efficacy and safety.
S. Yamada, T. Fujii, T. Yamamoto, H. Takami, I. Yoshioka, S. Yamaki, F. Sonohara, K. Shibuya, F. Motoi, S. Hirano, Y. Murakami, H. Inoue, M. Hayashi, K. Murotani, J. Kitayama, H. Ishikawa, Y. Kodera, M. Sekimoto, S. Satoi   +18 more
wiley   +1 more source

Recidiva de vasculitis asociada a anticuerpos anticitoplasma de neutrófilos en un paciente con trasplante renal

Nefrología, 2016
La afectación renal de las vasculitis asociadas a anticuerpos anticitoplasma de neutrófilos (ANCA) puede conducir a enfermedad renal crónica con necesidad de tratamiento renal sustitutivo.
Pedro García Cosmes, Pilar Fraile Gómez, Kamil Lewczuk, Marta Rodríguez González, Elena Ruiz Ferreras, Guadalupe Tabernero Fernández   +5 more
doaj   +1 more source

Comparison of the Peritoneal Cancer Index and Dutch region count as tools to stage patients with peritoneal metastases of colorectal cancer

BJS Open, Volume 4, Issue 6, Page 1153-1161, December 2020., 2020
This retrospective study compared two classification tools, the Dutch region count and the Peritoneal Cancer Index, for colorectal peritoneal metastases, and validated the results in a separate cohort. The region count was easier to apply, and may benefit doctors who refer patients to expert centres.
F. S. Verheij, C. Bakkers, W. J. van Eden, A. G. J. Aalbers, S. W. Nienhuijs, K. Jóźwiak, I. H. J. T. de Hingh, N. F. M. Kok   +7 more
wiley   +1 more source

Factors associated with metachronous metastases and survival in locally advanced and recurrent rectal cancer

BJS Open, Volume 4, Issue 6, Page 1172-1179, December 2020., 2020
Surgery for locally advanced and recurrent rectal cancer can achieve good survival outcomes. Some histopathological features significantly increase the number of metachronous metastases and shorten survival. Presentation with a synchronous metastasis that is treated successfully significantly increases the number of metachronous metastases and shortens
D. L. H. Baird, C. Kontovounisios, C. Simillis, G. Pellino, S. Rasheed, P. P. Tekkis   +5 more
wiley   +1 more source

Surgery for multiple endocrine neoplasia type 1‐related insulinoma: long‐term outcomes in a large international cohort

BJS (British Journal of Surgery), Volume 107, Issue 11, Page 1489-1499, October 2020., 2020
In this cohort of 96 patients with resected multiple endocrine neoplasia 1 (MEN1)‐related insulinomas, seven patients (7 per cent) developed postoperative persistent or recurrent hypoglycaemia after a median follow‐up of 8 years. The 10‐year hypoglycaemia‐free survival rate was 91 (95 per cent c.i. 80 to 96) per cent.
D. J. van Beek, S. Nell, H. M. Verkooijen, I. H. M. Borel Rinkes, G. D. Valk, (on behalf of the DutchMEN study group), M. R. Vriens, the International MEN1 Insulinoma Study Group, P. Goudet, A. Vella, D. Donegan, D. K. Bartsch, J. Manoharan, N. D. Perrier, I. Christakis, M. L. Brandi, R. Zarnegar, E. L. Postma, E. Kebebew, P. Nockel, L. Brunaud, J. D. Pasternak, W. P. Kluijfhout, C. Sturgeon, S. Giri, B. A. Bonsing, C. H. van Eijck, H. van Goor, R. H. J. de Kleine, E. J. Nieveen van Dijkum, C. H. C. Dejong   +30 more
wiley   +1 more source

Meta‐analysis of the impact of postoperative infective complications on oncological outcomes in colorectal cancer surgery

BJS Open, Volume 4, Issue 5, Page 737-747, October 2020., 2020
Postoperative infective complications have significant negative effects on oncological outcomes in colorectal cancer. Anastomotic leakage has a negative effect on every measured outcome. New registries should include oncological outcomes and complications to facilitate future research and optimize outcomes.
J. Lawler, M. Choynowski, K. Bailey, M. Bucholc, A. Johnston, M. Sugrue   +5 more
wiley   +1 more source

Supervivencia intracelular de cepas de Mycobacterium bovis de alta y baja frecuencia probado en un modelo de macrófagos bovinos

Revista Mexicana de Ciencias Pecuarias, 2021
Causada por Mycobacterium bovis, la tuberculosis bovina es una enfermedad que afecta al ganado y a otras especies, incluidos los humanos. M. bovis reside principalmente en macrófagos, por lo que la supervivencia de los bacilos dentro de los macrófagos ...
Alejandro Nava-Vargas, Feliciano Milián-Suazo, Germinal Jorge Cantó-Alarcón, José A. Gutiérrez-Pabello   +3 more
doaj   +1 more source

Ki67 expression at Kasai portoenterostomy as a prognostic factor in patients with biliary atresia

BJS Open, Volume 4, Issue 5, Page 873-883, October 2020., 2020
No consensus exists for predicting outcomes after Kasai portoenterostomy (KP) using liver histological findings. Ki67 (clone, MIB‐1) expression in liver parenchyma was measured by means of immunohistochemical staining of samples from five living donors and 35 patients with biliary atresia to assess its value in predicting KP outcomes.
D. Yoshii, Y. Inomata, Y. Komohara, K. Shimata, M. Honda, S. Hayashida, Y. Oya, H. Yamamoto, H. Yamamoto, Y. Sugawara, T. Hibi   +10 more
wiley   +1 more source

Early operative management in patients with adhesive small bowel obstruction: population‐based cost analysis

BJS Open, Volume 4, Issue 5, Page 914-923, October 2020., 2020
This population‐based cost–utility analysis compared early operative management (EOM) for adhesive small bowel obstruction (SBO) to the current standard of care of a trial of non‐operative management. Although EOM was more costly, it was associated with a significantly lower risk of recurrence and reduced exposure to the morbidity and costs associated ...
R. Behman, A. B. Nathens, P. Pechlivanoglou, P. Karanicolas, J. Jung, N. Look Hong   +5 more
wiley   +1 more source

Impact of extent of disease on 1‐year healthcare costs in patients who undergo cytoreductive surgery with hyperthermic intraperitoneal chemotherapy for colorectal peritoneal metastases: retrospective observational cohort study

BJS Open, Volume 4, Issue 5, Page 954-962, October 2020., 2020
Well selected patients with colorectal peritoneal metastases can be treated with curative intent by cytoreductive surgery with hyperthermic intraperitoneal chemotherapy. Treatment‐related healthcare costs are significantly increased among patients with extensive peritoneal disease, although the associated survival gain is limited.
B. J. L. Kooijman, J. E. K. R. Hentzen, C. S. van der Hilst, L. B. Been, R. J. van Ginkel, P. H. J. Hemmer, J. M. Klaase, S. Kruijff   +7 more
wiley   +1 more source