Results 51 to 60 of about 273,499 (304)

Abstracts From the 22nd Annual Health Care Systems Research Network Conference, April 13–16, 2016, Atlanta, Georgia

Journal of Patient-Centered Research and Reviews, 2016
This proceedings supplement includes selected abstracts presented at the 22nd annual conference of the Health Care Systems Research Network (HCSRN), held April 13–16, 2016, in Atlanta, Georgia.
Various authors
doaj   +1 more source

Automated tracking of a passive intramyocardial needle with off-resonance MRI: a feasibility study [PDF]

, 2008
Direct intramyocardial therapies aimed at treating myocardial regions affected by severe ischemia may benefit from CMR-guided interventional procedures. Although interventional MR approaches using active devices are considered to be the method of choice,
Aggelos K Katsaggelos, Debiao Li, Dharmakumar, Dharmakumar, Ioannis Koktzoglou, Koktzoglou, Rohan Dharmakumar, Sotirios A Tsaftaris   +7 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Multi-scale modelling of macromolecular conformational changes [PDF]

, 2009
Modelling protein flexibility and plasticity is computationally challenging but important for understanding the function of biological systems. Furthermore, it has great implications for the prediction of (macro) molecular complex formation.
Ahmed, Aqeel, Gohlke, Holger, Koller, Alrun N.   +2 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Abstracts From the 24th Annual Health Care Systems Research Network Conference, April 11–13, 2018, Minneapolis, Minnesota

Journal of Patient-Centered Research and Reviews, 2018
Founded in 1994, the Health Care Systems Research Network (HCSRN) is a consortium of 18 research centers that are housed in community-based health systems.
Various authors
doaj   +1 more source

NASA Patent Abstracts bibliography: A continuing bibliography. Section 1: Abstracts (supplement 21) Abstracts [PDF]

s are cited for 87 patents and applications introduced into the NASA scientific and technical information system during the period of January 1982 through June 1982.

core   +1 more source

Molecular similarity for machine learning in drug development : poster presentation [PDF]

, 2008
Poster presentation In pharmaceutical research and drug development, machine learning methods play an important role in virtual screening and ADME/Tox prediction.
Proschak, Ewgenij, Rupp, Matthias, Schneider, Gisbert (Prof. Dr.)   +2 more
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Abstracts from the 72nd Congress of the ESCVS, the European Society of CardioVascular and Endovascular Surgery

Medical Sciences Forum
The 72nd Annual International Congress of the European Society for Cardiovascular and Endovascular Surgery (ESCVS) 2024 in Istanbul, Turkey, marks a significant milestone in the advancement of cardiovascular surgery.
Ergun Demirsoy, Matthias Thielmann
doaj   +1 more source