Results 61 to 70 of about 273,499 (304)

NASA patent abstracts bibliography: A continuing bibliography. Section 1: Abstracts (supplement 32) [PDF]

open access: yes
s are provided for 136 patents and patent applications entered into the NASA scientific and technical information system during the period July through December 1987.

core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Abstracts From the 26th Annual Health Care Systems Research Network Conference, April 8–10, 2020

open access: yesJournal of Patient-Centered Research and Reviews, 2020
The Health Care Systems Research Network (HCSRN) is made up of community-based care delivery systems with a shared mission to improve health and health care through research.
Various authors
doaj   +1 more source

NASA patent abstracts bibliography: A continuing bibliography. Section 1: Abstracts (supplement 07) [PDF]

open access: yes
This bibliography is issued in two sections: Section 1 - Abstracts, and Section 2 - Indexes. This issue of the Abstract Section cites 158 patents and applications for patent introduced into the NASA scientific and technical information system during the

core   +1 more source

Dense gap-junction connections support dynamic Turing structures in the cortex [PDF]

open access: yes, 2007
The recent report by Fukuda et al [1] provides convincing evidence for dense gap-junction connectivity between inhibitory neurons in the cat visual cortex, each neuron making 60 +/- 12 gap-junction dendritic connections with neurons in both the same and ...
DAlistair DAlistairSteyn-Ross   +4 more
core   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Abstracts From the 25th Annual Health Care Systems Research Network Conference, April 8–10, 2019, Portland, Oregon

open access: yesJournal of Patient-Centered Research and Reviews, 2019
The Health Care Systems Research Network (HCSRN) is made up of nonprofit health systems with embedded research departments whose scientists are dedicated to public domain research.
Various authors
doaj   +1 more source

NASA patent abstracts bibliography: A continuing bibliography. Section 1: Abstracts (supplement 41) [PDF]

open access: yes
s are provided for 131 patents and patent applications entered into the NASA scientific and technical information system during the period Jan. 1992 through Jun. 1992.

core   +1 more source

Towards a computational model for stimulation of the Pedunculopontine nucleus [PDF]

open access: yes, 2009
The pedunculopontine nucleus (PPN) has recently been suggested as a new therapeutic target for deep brain stimulation (DBS) in patients suffering from Parkinson's disease, particularly those with severe gait and postural impairment [1].
Gils, Stephan A. van   +3 more
core   +4 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

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