Results 101 to 110 of about 1,805,326 (286)
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
The Effect of Supplemental Health Insurance on Family Quality of Life
Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2016 BACKGROUND AND OBJECTIVE: The essence of insurance is compensating damages and replacing uncertainty with peace of mind; and insurance, as a way of dealing with risk, is a response to insecure and risky situations.
Z Hajitabar, AA Nasiripour, MA Jahani
doaj
Supplemental nursing staff´s experiences at a Spanish hospital: Qualitative phenomenology research
Revista da Escola de Enfermagem da USP, 2014 The objective of this study was to describe the Supplemental Nursing Staff´s experiences at different hospital units. A qualitative phenomenological approach was conducted; a purposeful and theoretical sampling was implemented with supplemental nursing ...
Yolanda Raquel Lapeña-Moñux +4 more
doaj +2 more sources
Climate change and rainfed agriculture: how to extend the campaign and improve the Burkinabe agricultural production? [P61] [PDF]
, 2015 In Burkina Faso, agriculture is the main activity of rural households. It occupies more than two thirds of the workforce and contributes more than a third to gross domestic product.
Barbier, Bruno +4 more
core
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Supplemental Maxillary Permanent Central Incisor or Macrodontia of Lateral Incisor! A Diagnostic Challenge [PDF]
Journal of Clinical and Diagnostic Research, 2016 Navin Hadadi Krishnamurthy +3 more
doaj +1 more source
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
Effects of Artificial Light Treatments on Growth, Mineral Composition, Physiology, and Pigment Concentration in Dieffenbachia maculata “Compacta” Plants [PDF]
, 2019 Specific wavebands may allow precise control of plant growth. However, light sources must be carefully evaluated before the large-scale use of supplemental light sources can be implemented.
Almansa Espín, Eva María +3 more
core +1 more source