Results 241 to 250 of about 1,805,326 (286)

Deviations from additivity in APOE4-mediated late-onset Alzheimer's disease risk across races and ethnicities. [PDF]

Hum Genet
Durodoye RO, Ciesielski TH, Benchek P, Bartlett J, Zhu X, Liu S, Naj A, Kunkle B, Schellenberg GD, Mayeux R, Farrer L, Wang LS, Pericak-Vance MA, Rajabli F, Tosto G, Haines JL, Bush WS, Williams SM.   +17 more
europepmc   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Evaluating ChatGPT's Ability to Answer Common Parent Questions on Avascular Necrosis in Children. [PDF]

HSS J
Smith GB, Hofmann GH, Gussner AV, Duru NO, Laureano TA, Meadows MC, Chan C, Shea KG.   +7 more
europepmc   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

LED lighting and exogenous cytokinin enhance budbreak and winter growth of 'Washington' navel orange in the nursery. [PDF]

Front Plant Sci
de Carvalho DU, Bisi RB, Bowman KD, Albrecht U.   +3 more
europepmc   +1 more source

Bispecific antibodies and CAR T cells targeting a TP53 mutation-associated neoantigen show discordant affinity requirements. [PDF]

J Clin Invest
DiNapoli SR, Wright KM, Mog BJ, Pearlman AH, Nichakawade TD, Marcou N, Hsiue EH, Hwang MS, Douglass J, Liu Q, Watson E, Dal Molin M, Cohen JD, Popoli M, Paul S, Konig MF, Wyhs N, Azurmendi PA, Glavaris S, Ge J, Awosika TO, Liu J, Gabrielson KL, Gabelli SB, Pardoll DM, Bettegowda C, Papadopoulos N, Kinzler KW, Zhou S, Vogelstein B.   +29 more
europepmc   +1 more source

Novel trinucleotide mRNA capping reagents: improved synthetic route and efficient cotranscriptional incorporation in mRNA. [PDF]

RNA
Xu C, Cousins R, Ilichev I, Ceja J, Ludford P, Begoyan V, Turner M, Santos M, Vo C, Rezvani F, Ujita A, Henderson J, Houston M, Zhao C, Lebedev AV.   +14 more
europepmc   +1 more source

Burden and Trends of Nasopharyngeal Cancer Among Younger People in the Western Pacific Region, 1990 to 2021: Findings from the 2021 Global Burden of Disease Study. [PDF]

J Otolaryngol Head Neck Surg
Zhou L, Ma G, Jia W, Zhang Y, Wu L, Ye Y, Liu D, Li X.   +7 more
europepmc   +1 more source

PD-L1 expression on circulating tumor cells for predicting clinical outcomes in patients with hepatocellular carcinoma receiving PD-(L)1 blockade and targeted therapy. [PDF]

J Immunother Cancer
Gong C, You S, Zhang Q, Yang Z, Bi X, Zhao H, Sun Y, Zhou J, Rong W, Zhao J, Zhang K, Zhou A, Zhang W, Zhang W.   +13 more
europepmc   +1 more source