Results 31 to 40 of about 254,146 (258)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

ALIMENTAÇÃO DE CRIANÇAS NOS PRIMEIROS DOIS ANOS DE VIDA

Revista Paulista de Pediatria
RESUMO Objetivo: Avaliar a frequência do aleitamento materno e a introdução da alimentação complementar em crianças de zero a 24 meses. Métodos: Estudo transversal de base populacional, composto por amostra representativa de crianças menores de 24 ...
Wanessa Casteluber Lopes, Fúlvia Karine Santos Marques, Camila Ferreira de Oliveira, Jéssica Alkmim Rodrigues, Marise Fagundes Silveira, Antônio Prates Caldeira, Lucinéia de Pinho   +6 more
doaj   +1 more source

Feeding Supplementary Feeding on Baby Constipation In Bamboo Field Village

International Journal of Clinical Inventions and Medical Sciences (IJCIMS), 2023
Constipation is a condition in which the stool hardens which makes it difficult to pass through the anus, and causes discomfort in the rectum. Babies who experience constipation are characterized by crying, whining in pain and the face turning red before defecation.
Rizky Andriani Bakara, Arva Rochmawati
openaire   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Winter insomnia: How weather conditions and supplementary feeding affect the brown bear activity in a long-term study

Global Ecology and Conservation, 2019
Climate change and anthropogenic food subsidies affect wildlife everywhere in the world. We used a 30-year set of data on winter observations of brown bear Ursus arctos to investigate the effects of weather and supplementary feeding on bear winter ...
Katarzyna Bojarska, Szymon Drobniak, Zbigniew Jakubiec, Ewa Zyśk-Gorczyńska   +3 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

EVALUATING OF SUPPLEMENTARY FEEDING IN BREASTFED INFANTS

Grail of Science, 2023
The aim of the study: to assess supplementary feeding in breastfed neonate, evaluate infant and maternal indications for supplementation in healthy infants. Methods. An anonymous voluntary survey about supplementary feeding of 50 women who has breastfed children and visited the hospital for various reasons, not related to breastfeeding.
V. Oliinyk, L. Yushchenko, O. Kuleshov, L. Kotsur   +3 more
openaire   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source