Results 211 to 220 of about 2,455,219 (389)

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Supplement Note [PDF]

Prion, 2016
openaire   +2 more sources

Effect of calcium and vitamin D supplementation on bone density in men and women 65 years of age or older.

New England Journal of Medicine, 1997
B. Dawson-Hughes, S. Harris, E. Krall, G. Dallal   +3 more
semanticscholar   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Effects of Vitamin C and/or E Supplementation on Glycemic Control and Cardiovascular Risk Factors in Type 2 Diabetes: A Systematic Review and Subgroup Meta-analysis. [PDF]

Nutr Rev
Aragón-Vela J, Huertas JR, Casuso RA.
europepmc   +1 more source

Lack of effect of long-term supplementation with beta carotene on the incidence of malignant neoplasms and cardiovascular disease.

New England Journal of Medicine, 1996
C. Hennekens, J. Buring, J. Manson, M. Stampfer, B. Rosner, N. Cook, C. Belanger, F. LaMotte, J. Gaziano, P. Ridker, W. Willett, R. Peto   +11 more
semanticscholar   +1 more source

Supplemental benefit of an angiotensin receptor blocker in hypertensive patients with stable heart failure using olmesartan (SUPPORT) trial—Rationale and design [PDF]

, 2013
Yasuhiko Sakata, Kotaro Nochioka, Masanobu Miura, Tsuyoshi Takada, Soichiro Tadaki, Satoshi Miyata, Nobuyuki Shiba, Hiroaki Shimokawa   +7 more
openalex   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Supplementary L-arginine can enhance reproductive parameters and outcomes in large mammals. [PDF]

Front Vet Sci
Ohrt MM, Ing NH.
europepmc   +1 more source

Chromium propionate supplementation during the peripartum period interacts with starch source fed postpartum: Production responses during the immediate postpartum and carryover periods [PDF]

, 2016
Richard Rockwell, Michael S. Allen
openalex   +1 more source