Results 181 to 190 of about 310,044 (307)

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

A multidimensional procurement literacy instrument: Development and validation among undergraduate procurement students in Ghana. [PDF]

PLoS One
Oppong PB, Ofori D, Wunu P, Nyamah EY, Nyamah EY, Boateng JKGA, Agyapong GKQ.   +6 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Risk of Porcine reproductive and respiratory syndrome virus introduction into Danish pig farms: a register-based study. [PDF]

Porcine Health Manag
Fertner M, Boldsen SK, Weber NR, Pedersen JH, Toft N.   +4 more
europepmc   +1 more source

Service-dominant strategic sourcing : value creation versus cost saving [PDF]

, 2016
A Cox, A Cox, B Thalheim, C Bowman, C Helfat, D Teece, G Poels, I Ng, IJ Chen, J Jacobs, JB Barney, JB Barney, K Peffers, L Rafati, L Rafati, LM Ellram, M Zollo, MA Akaka, P Kraljic, P Maglio, PH Anderson, R Eltantawy, RF Lusch, S Barile, S Beer, S Beer, SL Vargo, SL Vargo, SL Vargo, SL Vargo, SL Vargo   +30 more
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Supplier Evaluation and Selection - A Review

International Journal for Research in Applied Science and Engineering Technology, 2019
MARY WALOWE MWADULO, SAMSON WANJALA MUNIALO   +1 more
openaire   +3 more sources

Prioritized Aczel-Alsina aggregation operators under p, q-quasirung orthopair fuzzy environment for sustainable supplier selection in new energy vehicle industry. [PDF]

Sci Rep
Ali J, Al-Kenani AN, Syam MI.
europepmc   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Agile method for planning a smart classroom. [PDF]

MethodsX
Pate Santos GN, Lucena CJP.
europepmc   +1 more source