Results 111 to 120 of about 246,803 (306)

Incentives for Sabotage in Vertically Related Industries [PDF]

open access: yes
We show that the incentives a vertically integrated supplier may have to disadvantage or "sabotage" the activities of downstream rivals vary with both the type of sabotage and the nature of downstream competition.
David E. M. Sappington, David Mandy
core  

Economising, Strategising and the Vertical Boundaries of the Firm [PDF]

open access: yes, 2015
Publisher ...
Leahy, Dermot, Montagna, Catia
core  

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Structural Modeling Based on Supply Chain Integration in Relation to Supply Chain Risk, Product Quality and Innovation Capability

open access: yesمدیریت بهره وری
This study aims to investigate the unique features of the food supply chain, examining the impact of food supply chain integration, consisting of internal integration, supplier and customer, the quality of food products and product innovation capability.
Abolfazl Kazzazi, Amir Mohammad khani
doaj  

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Managing Supplier Integration into Product Development: A Literature Review and Conceptual Model [PDF]

open access: yes
Industrial clusters, Regional agglomerations, Technological learning, Technological capability, Knowledge spillovers, Regional innovation ...
Echtelt, F.E.A. van, Wynstra, J.Y.F.
core  

Buyer-supplier partnership in agile supply chains: A conceptual view [PDF]

open access: yes, 2010
The purpose of this paper focuses on achieving agility within the supply chain and seeks to examine the impact of developing an integrated buyer-supplier partnership on achieving agility.
El-Tawy, Nesrine, Gallear, D
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

AN EXPLORATORY APPROACH TO INTEGRATION OF BUSINESS PRACTICES IN SUPPLY CHAIN MANAGEMENT [PDF]

open access: yesAnnals of the University of Oradea: Economic Science, 2014
Literature on supply chain management focuses increasingly on the topic of supply chain integration. Morash and Bowersox (1989) show that integration links relationships, activities, functions, processes and locations.
Constangioara Alexandru, , ,
doaj  

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