Results 161 to 170 of about 4,298,127 (373)

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

An Integration of HF-AHP and ARAS Techniques in Supplier Selection: A Case Study in Waste Water Treatment Facility

, 2019
Aşkın Özdağoğlu, Kevser Yılmaz, Elif YÜCE   +2 more
openalex   +1 more source

Integration of trust supplier with supply chain capability and application towards supply chain performance: Minimarket competition during the Covid-19 pandemic

, 2023
J.E. Sutanto, Denpharanto Agung Krisprimandoyo, Mochamad Ali Imron   +2 more
openalex   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Leveraging Big Data Analytics Capability and Green Supplier Integration for Improved Economic, Social, and Environmental Sustainability in Manufacturing Companies

SAGE Open
With increasing global concerns about business continuity, societal welfare, and environmental degradation, corporate sustainability has gained significant academic attention.
Jie Cheng, Ni Sun, Ya-Nan Zou, Ke-Bin Lu, Dan-Dan Wang   +4 more
doaj   +1 more source

Pipeline politics and energy (in)security in Central and South-Eastern Europe [PDF]

, 2016
No abstract ...
Butler, Eamonn
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Contractual Dimensions and Buyer-Supplier Perceived Risk: the Moderating Role of Information Technology Integration. [PDF]

, 2019
Yuting Wang, Zhao Cai, Hefu Liu, Qian Huang   +3 more
openalex   +1 more source

The role of supply chain integration in achieving competitive advantage: A study of UK automobile manufacturers [PDF]

, 2016
The competitive nature of the global automobile industry has resulted in a battle for efficiency and consistency in supply chain management (SCM). For manufacturers, the diversified network of suppliers represents more than just a production system; it ...
Akkaranggoon, Supalak, Garza-Reyes, Jose Arturo, Kumar, Vikas, Kumari, Archana, Ngo, Hieu Van   +4 more
core   +1 more source